Identity
HGNC
LOCATION
3p24.3
LOCUSID
ALIAS
DAZH,DAZL1,DAZLA,SPGYLA
FUSION GENES
Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, contribute in submission tool
Other Information
Locus ID:
NCBI: 1618
MIM: 601486
HGNC: 2685
Ensembl: ENSG00000092345
Variants:
dbSNP: 1618
ClinVar: 1618
TCGA: ENSG00000092345
COSMIC: DAZL
RNA/Proteins
| Gene ID | Transcript ID | Uniprot |
|---|---|---|
| ENSG00000092345 | ENST00000250863 | Q92904 |
| ENSG00000092345 | ENST00000399444 | Q92904 |
| ENSG00000092345 | ENST00000399444 | A0A140VK77 |
| ENSG00000092345 | ENST00000454457 | E7EV40 |
Expression (GTEx)
Protein levels (Protein atlas)
References
| Pubmed ID | Year | Title | Citations |
|---|---|---|---|
| 38588931 | 2024 | A novel cancer-germline gene DAZL promotes progression and cisplatin resistance of non-small cell lung cancer by upregulating JAK2 and MCM8. | 0 |
| 38588931 | 2024 | A novel cancer-germline gene DAZL promotes progression and cisplatin resistance of non-small cell lung cancer by upregulating JAK2 and MCM8. | 0 |
| 36434389 | 2023 | Association of DAZL polymorphisms and DAZ deletion with male infertility: a systematic review and meta-analysis. | 0 |
| 36434389 | 2023 | Association of DAZL polymorphisms and DAZ deletion with male infertility: a systematic review and meta-analysis. | 0 |
| 36273819 | 2022 | DAZL regulates proliferation of human primordial germ cells by direct binding to precursor miRNAs and enhances DICER processing activity. | 3 |
| 36273819 | 2022 | DAZL regulates proliferation of human primordial germ cells by direct binding to precursor miRNAs and enhances DICER processing activity. | 3 |
| 33542261 | 2021 | The marker of alkyl DNA base damage, N7-methylguanine, is associated with semen quality in men. | 2 |
| 34653405 | 2021 | Direct reprogramming of human Sertoli cells into male germline stem cells with the self-renewal and differentiation potentials via overexpressing DAZL/DAZ2/BOULE genes. | 5 |
| 33542261 | 2021 | The marker of alkyl DNA base damage, N7-methylguanine, is associated with semen quality in men. | 2 |
| 34653405 | 2021 | Direct reprogramming of human Sertoli cells into male germline stem cells with the self-renewal and differentiation potentials via overexpressing DAZL/DAZ2/BOULE genes. | 5 |
| 32682409 | 2020 | Suppressing Dazl modulates tumorigenicity and stemness in human glioblastoma cells. | 9 |
| 32682409 | 2020 | Suppressing Dazl modulates tumorigenicity and stemness in human glioblastoma cells. | 9 |
| 28364521 | 2017 | RNA immunoprecipitation identifies novel targets of DAZL in human foetal ovary. | 14 |
| 28388287 | 2017 | In silico analysis of non-synonymous single nucleotide polymorphisms in human DAZL gene associated with male infertility. | 11 |
| 28364521 | 2017 | RNA immunoprecipitation identifies novel targets of DAZL in human foetal ovary. | 14 |
Citation
Dessen P
DAZL (deleted in azoospermia like)
Atlas Genet Cytogenet Oncol Haematol. 2012-11-01
Online version: http://atlasgeneticsoncology.org/gene/52990/dazl-(deleted-in-azoospermia-like)
