Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, contribute in submission tool
Other Information
Locus ID:
NCBI: 55789
MIM: 616073
HGNC: 24902
Ensembl: ENSG00000035499
Variants:
dbSNP: 55789
ClinVar: 55789
TCGA: ENSG00000035499
COSMIC: DEPDC1B
RNA/Proteins
| Gene ID | Transcript ID | Uniprot |
|---|---|---|
| ENSG00000035499 | ENST00000265036 | Q8WUY9 |
| ENSG00000035499 | ENST00000453022 | Q8WUY9 |
| ENSG00000035499 | ENST00000512078 | D6RIB0 |
| ENSG00000035499 | ENST00000512452 | D6RDV9 |
Expression (GTEx)
Pathways
| Pathway | Source | External ID |
|---|---|---|
| Signal Transduction | REACTOME | R-HSA-162582 |
| Signaling by Rho GTPases | REACTOME | R-HSA-194315 |
| Rho GTPase cycle | REACTOME | R-HSA-194840 |
Protein levels (Protein atlas)
References
| Pubmed ID | Year | Title | Citations |
|---|---|---|---|
| 37979396 | 2024 | DEPDC1B enhances malignant phenotypes of multiple myeloma through upregulating CCNB1 and inhibiting p53 signaling pathway. | 0 |
| 38614125 | 2024 | ZNF146 regulates cell cycle progression via TFDP1 and DEPDC1B in ovarian cancer cells. | 0 |
| 38940035 | 2024 | DEPDC1B is a Novel Direct Target of B-Myb and Contributes to Malignant Progression and Immune Infiltration in Lung Adenocarcinoma. | 0 |
| 37979396 | 2024 | DEPDC1B enhances malignant phenotypes of multiple myeloma through upregulating CCNB1 and inhibiting p53 signaling pathway. | 0 |
| 38614125 | 2024 | ZNF146 regulates cell cycle progression via TFDP1 and DEPDC1B in ovarian cancer cells. | 0 |
| 38940035 | 2024 | DEPDC1B is a Novel Direct Target of B-Myb and Contributes to Malignant Progression and Immune Infiltration in Lung Adenocarcinoma. | 0 |
| 36016512 | 2023 | DEPDC1B promotes colorectal cancer via facilitating cell proliferation and migration while inhibiting apoptosis. | 3 |
| 36913076 | 2023 | Circ_0005276 Promotes Prostate Cancer Progression Through the Crosstalk of miR-128-3p/DEPDC1B Axis. | 0 |
| 37203403 | 2023 | DEPDC1B is involved in the proliferation, metastasis, cell cycle arrest and apoptosis of colon cancer cells by regulating NUP37. | 3 |
| 37642235 | 2023 | DEPDC1B-mediated USP5 deubiquitination of β-catenin promotes breast cancer metastasis by activating the wnt/β-catenin pathway. | 1 |
| 36016512 | 2023 | DEPDC1B promotes colorectal cancer via facilitating cell proliferation and migration while inhibiting apoptosis. | 3 |
| 36913076 | 2023 | Circ_0005276 Promotes Prostate Cancer Progression Through the Crosstalk of miR-128-3p/DEPDC1B Axis. | 0 |
| 37203403 | 2023 | DEPDC1B is involved in the proliferation, metastasis, cell cycle arrest and apoptosis of colon cancer cells by regulating NUP37. | 3 |
| 37642235 | 2023 | DEPDC1B-mediated USP5 deubiquitination of β-catenin promotes breast cancer metastasis by activating the wnt/β-catenin pathway. | 1 |
| 34983303 | 2022 | DEP domain containing 1B (DEPDC1B) exerts the tumor promoter in hepatocellular carcinoma through activating p53 signaling pathway via kinesin family member 23 (KIF23). | 2 |
Citation
Dessen P
DEPDC1B (DEP domain containing 1B)
Atlas Genet Cytogenet Oncol Haematol. 2012-11-01
Online version: http://atlasgeneticsoncology.org/gene/52992/depdc1b-(dep-domain-containing-1b)
