FXYD6 (FXYD domain containing ion transport regulator 6)

2012-11-01  

Identity

HGNC
LOCATION
11q23.3
LOCUSID
ALIAS
-
FUSION GENES

Other Information

Locus ID:

NCBI: 53826
MIM: 606683
HGNC: 4030
Ensembl: ENSG00000137726

Variants:

dbSNP: 53826
ClinVar: 53826
TCGA: ENSG00000137726
COSMIC: FXYD6

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000137726ENST00000260282Q9H0Q3
ENSG00000137726ENST00000260282A0A024R3J8
ENSG00000137726ENST00000524656Q9H0Q3
ENSG00000137726ENST00000524656A0A024R3J8
ENSG00000137726ENST00000524841E9PJ02
ENSG00000137726ENST00000526014Q9H0Q3
ENSG00000137726ENST00000526014A0A024R3J8
ENSG00000137726ENST00000527717Q9H0Q3
ENSG00000137726ENST00000527717A0A024R3J8
ENSG00000137726ENST00000529335E9PHZ3
ENSG00000137726ENST00000530956Q9H0Q3
ENSG00000137726ENST00000530956A0A024R3J8
ENSG00000137726ENST00000539526Q9H0Q3
ENSG00000137726ENST00000539526A0A024R3J8
ENSG00000137726ENST00000584230E9PJ02
ENSG00000137726ENST00000584394J3QKN1

Expression (GTEx)

0
50
100
150
200
250
300

Pathways

PathwaySourceExternal ID
Muscle contractionREACTOMER-HSA-397014
Transmembrane transport of small moleculesREACTOMER-HSA-382551
Ion channel transportREACTOMER-HSA-983712
Ion transport by P-type ATPasesREACTOMER-HSA-936837
Cardiac conductionREACTOMER-HSA-5576891
Ion homeostasisREACTOMER-HSA-5578775

Protein levels (Protein atlas)

Not detected
Low
Medium
High

References

Pubmed IDYearTitleCitations
380936222023Identification of FXYD6 as the novel biomarker for glioma based on differential expression and DNA methylation.2
380936222023Identification of FXYD6 as the novel biomarker for glioma based on differential expression and DNA methylation.2
332316122020FXYD protein isoforms differentially modulate human Na/K pump function.12
332316122020FXYD protein isoforms differentially modulate human Na/K pump function.12
263027712016MicroRNA-137 is downregulated in human osteosarcoma and regulates cell proliferation and migration through targeting FXYD6.17
263027712016MicroRNA-137 is downregulated in human osteosarcoma and regulates cell proliferation and migration through targeting FXYD6.17
247152682014FXYD6: a novel therapeutic target toward hepatocellular carcinoma.23
247152682014FXYD6: a novel therapeutic target toward hepatocellular carcinoma.23
212162382011A novel replicated association between FXYD6 gene and schizophrenia.6
219837302011[A family-based association study of FXYD6 gene polymorphisms and schizophrenia].2
212162382011A novel replicated association between FXYD6 gene and schizophrenia.6
219837302011[A family-based association study of FXYD6 gene polymorphisms and schizophrenia].2
201493922010No association between the FXYD6 gene and schizophrenia in the Chinese Han population.2
201493922010No association between the FXYD6 gene and schizophrenia in the Chinese Han population.2
204680772010Failure to confirm genetic association of the FXYD6 gene with schizophrenia: the Japanese population and meta-analysis.4

Citation

Dessen P

FXYD6 (FXYD domain containing ion transport regulator 6)

Atlas Genet Cytogenet Oncol Haematol. 2012-11-01

Online version: http://atlasgeneticsoncology.org/gene/53003/fxyd6-(fxyd-domain-containing-ion-transport-regulator-6)