SLTM (SAFB like transcription modulator)

2012-11-01  

Identity

HGNC
SLTM
LOCATION
15q22.1
LOCUSID
79811
ALIAS
Met
FUSION GENES
Show Gene Fusions

Other Information

Locus ID:

NCBI: 79811
HGNC: 20709
Ensembl: ENSG00000137776

Variants:

dbSNP: 79811
ClinVar: 79811
TCGA: ENSG00000137776
COSMIC: SLTM

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000137776ENST00000249736H7BXE3
ENSG00000137776ENST00000380516Q9NWH9
ENSG00000137776ENST00000432750H7C3F4
ENSG00000137776ENST00000492526H0YMR6
ENSG00000137776ENST00000557791H0YMM0
ENSG00000137776ENST00000557924H0YLW7
ENSG00000137776ENST00000558486H0YLE6
ENSG00000137776ENST00000558756H0YKU6
ENSG00000137776ENST00000559261H0YMW8
ENSG00000137776ENST00000559305H0YLW7
ENSG00000137776ENST00000559880H0YL55
ENSG00000137776ENST00000560494H0YKH2
ENSG00000137776ENST00000560682H0YNF3
ENSG00000137776ENST00000628684H0YLW7

Expression (GTEx)

0
10
20
30
40
50
60
70
80
90
Adipose - Subcutaneous
Adipose - Visceral
Adrenal Gland
Artery - Aorta
Artery - Tibial
Bladder
Brain - Amygdala
Brain - Anterior cingulate cortex
Brain - Caudate
Brain - Cerebellar Hemisphere
Brain - Cerebellum
Brain - Cortex
Brain - Frontal Cortex
Brain - Hippocampus
Brain - Hypothalamus
Brain - Nucleus accumbens
Brain - Putamen
Brain - Spinal cord
Brain - Substantia nigra
Breast - Mammary Tissue
Cells - Cultured fibroblasts
Cells - EBV - transformed lymphocytes
Cervix - Ectocervix
Cervix - Endocervix
Colon - Sigmoid
Colon - Transverse
Esophagus - Gastroesophageal Junction
Esophagus - Mucosa
Esophagus - Muscularis
Fallopian Tube
Heart - Atrial Appendage
Heart - Left Ventricle
Kidney - Cortex
Kidney - Medulla
Liver
Lung
Minor Salivary Gland
Muscle - Skeletal
Nerve - Tibial
Ovary
Pancreas
Pituitary
Prostate
Skin - Not Sun Exposed
Skin - Sun Exposed
Small Intestine - Terminal Ileum
Spleen
Stomach
Testis
Thyroid
Uterus
Vagina
Whole Blood

Protein levels (Protein atlas)

Not detected
Low
Medium
High
cerebral cortex
cerebellum
hippocampus
caudate
thyroid gland
parathyroid gland
adrenal gland
nasopharynx
lung
oral mucosa
salivary gland
esophagus
stomach 1
stomach 2
duodenum
small intestine
colon
rectum
liver
gallbladder
pancreas
kidney
urinary bladder
testis
epididymis
seminal vesicle
prostate
vagina
ovary
fallopian tube
endometrium 1
endometrium 2
cervix, uterine
placenta
breast
heart muscle
smooth muscle
skeletal muscle
soft tissue 1
soft tissue 2
adipose tissue
skin 1
skin 2
appendix
spleen
lymph node
tonsil
bone marrow

References

Pubmed IDYearTitleCitations
379960582024SPOP promotes CREB5 ubiquitination to inhibit MET signaling in liver cancer.0
381106662024MET exon 14 skipping mutation drives cancer progression and recurrence via activation of SMAD2 signalling.1
384705432024Deubiquitinase BRCC3 promotes the migration, invasion and EMT progression of colon adenocarcinoma by stabilizing MET expression.0
379960582024SPOP promotes CREB5 ubiquitination to inhibit MET signaling in liver cancer.0
381106662024MET exon 14 skipping mutation drives cancer progression and recurrence via activation of SMAD2 signalling.1
384705432024Deubiquitinase BRCC3 promotes the migration, invasion and EMT progression of colon adenocarcinoma by stabilizing MET expression.0
368571812023Plexin-B3 expression stimulates MET signaling, breast cancer stem cell specification, and lung metastasis.3
369355202023Circular RNA SLTM as a miR-421-competing endogenous RNA to mediate HMGB2 expression stimulates apoptosis and inflammation in arthritic chondrocytes.0
371401692023Long noncoding RNA FTX promotes epithelial-mesenchymal transition of epithelial ovarian cancer through modulating miR-7515/TPD52 and activating Met/Akt/mTOR.1
371501402023Lack of correlation between MET and PD-L1 expression in non-small cell lung cancer revealed by comparative study of matched biopsies and surgical resection samples.1
371887382023A DNA-PK phosphorylation site on MET regulates its signaling interface with the DNA damage response.2
377725832023Impact of SMAD2 and MET Expression on Lymph Node Metastasis of HER2-positive Gastric Cancer Cells.0
368571812023Plexin-B3 expression stimulates MET signaling, breast cancer stem cell specification, and lung metastasis.3
369355202023Circular RNA SLTM as a miR-421-competing endogenous RNA to mediate HMGB2 expression stimulates apoptosis and inflammation in arthritic chondrocytes.0
371401692023Long noncoding RNA FTX promotes epithelial-mesenchymal transition of epithelial ovarian cancer through modulating miR-7515/TPD52 and activating Met/Akt/mTOR.1

Citation

Dessen P

SLTM (SAFB like transcription modulator)

Atlas Genet Cytogenet Oncol Haematol. 2012-11-01

Online version: http://atlasgeneticsoncology.org/gene/53047/sltm-(safb-like-transcription-modulator)