Identity
HGNC
LOCATION
1p13.3
LOCUSID
ALIAS
DCAL,IRBIT,PPP1R78,PRO0233,XPVKONA
FUSION GENES
Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, contribute in submission tool
Other Information
Locus ID:
NCBI: 10768
MIM: 607826
HGNC: 344
Ensembl: ENSG00000168710
Variants:
dbSNP: 10768
ClinVar: 10768
TCGA: ENSG00000168710
COSMIC: AHCYL1
RNA/Proteins
| Gene ID | Transcript ID | Uniprot |
|---|---|---|
| ENSG00000168710 | ENST00000359172 | O43865 |
| ENSG00000168710 | ENST00000369799 | O43865 |
| ENSG00000168710 | ENST00000369799 | A0A024R0A8 |
| ENSG00000168710 | ENST00000393614 | O43865 |
Expression (GTEx)
Pathways
Protein levels (Protein atlas)
References
| Pubmed ID | Year | Title | Citations |
|---|---|---|---|
| 38294692 | 2024 | NRAS Mutant Dictates AHCYL1-Governed ER Calcium Homeostasis for Melanoma Tumor Growth. | 0 |
| 38294692 | 2024 | NRAS Mutant Dictates AHCYL1-Governed ER Calcium Homeostasis for Melanoma Tumor Growth. | 0 |
| 35218773 | 2022 | Unbiased proteomic profiling reveals the IP3R modulator AHCYL1/IRBIT as a novel interactor of microtubule-associated protein tau. | 2 |
| 35218773 | 2022 | Unbiased proteomic profiling reveals the IP3R modulator AHCYL1/IRBIT as a novel interactor of microtubule-associated protein tau. | 2 |
| 33355889 | 2021 | Adenosylhomocysteinase like 1 interacts with nonstructural 5A and regulates hepatitis C virus propagation. | 2 |
| 33727633 | 2021 | Both IRBIT and long-IRBIT bind to and coordinately regulate Cl(-)/HCO(3)(-) exchanger AE2 activity through modulating the lysosomal degradation of AE2. | 3 |
| 33355889 | 2021 | Adenosylhomocysteinase like 1 interacts with nonstructural 5A and regulates hepatitis C virus propagation. | 2 |
| 33727633 | 2021 | Both IRBIT and long-IRBIT bind to and coordinately regulate Cl(-)/HCO(3)(-) exchanger AE2 activity through modulating the lysosomal degradation of AE2. | 3 |
| 31366495 | 2019 | Low IRBIT Levels Are Associated With Chemo-resistance in Gastric Cancer Patients. | 2 |
| 31366495 | 2019 | Low IRBIT Levels Are Associated With Chemo-resistance in Gastric Cancer Patients. | 2 |
| 30377224 | 2018 | Modulation of Cl(-) signaling and ion transport by recruitment of kinases and phosphatases mediated by the regulatory protein IRBIT. | 7 |
| 30377224 | 2018 | Modulation of Cl(-) signaling and ion transport by recruitment of kinases and phosphatases mediated by the regulatory protein IRBIT. | 7 |
| 28647132 | 2017 | Mutations in S-adenosylhomocysteine hydrolase (AHCY) affect its nucleocytoplasmic distribution and capability to interact with S-adenosylhomocysteine hydrolase-like 1 protein. | 7 |
| 28647132 | 2017 | Mutations in S-adenosylhomocysteine hydrolase (AHCY) affect its nucleocytoplasmic distribution and capability to interact with S-adenosylhomocysteine hydrolase-like 1 protein. | 7 |
| 27455993 | 2016 | Combining Unique Multiplex Gateway Cloning and Bimolecular Fluorescence Complementation (BiFC) for High-Throughput Screening of Protein-Protein Interactions. | 7 |
Citation
Dessen P
AHCYL1 (adenosylhomocysteinase like 1)
Atlas Genet Cytogenet Oncol Haematol. 2012-12-01
Online version: http://atlasgeneticsoncology.org/gene/53083/ahcyl1-(adenosylhomocysteinase-like-1)
