ADAM28 (ADAM metallopeptidase domain 28)

2012-12-01  

Identity

HGNC
LOCATION
8p21.2
LOCUSID
ALIAS
ADAM
FUSION GENES

Other Information

Locus ID:

NCBI: 10863
MIM: 606188
HGNC: 206
Ensembl: ENSG00000042980

Variants:

dbSNP: 10863
ClinVar: 10863
TCGA: ENSG00000042980
COSMIC: ADAM28

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000042980ENST00000265769Q9UKQ2
ENSG00000042980ENST00000437154Q9UKQ2
ENSG00000042980ENST00000437154A0A384NKT9
ENSG00000042980ENST00000518326H0YBQ8
ENSG00000042980ENST00000520448E5RGY1
ENSG00000042980ENST00000521629H0YBG8
ENSG00000042980ENST00000523379E5RJQ1

Expression (GTEx)

0
5
10
15
20
25
30

Protein levels (Protein atlas)

Not detected
Low
Medium
High

References

Pubmed IDYearTitleCitations
360545592022LncRNA NEAT1 induces autophagy through the miR-128-3p/ADAM28 axis to suppress apoptosis of nonsmall-cell lung cancer.3
360545592022LncRNA NEAT1 induces autophagy through the miR-128-3p/ADAM28 axis to suppress apoptosis of nonsmall-cell lung cancer.3
336757842021ADAM28 from both endothelium and gastric cancer cleaves von Willebrand Factor to eliminate von Willebrand Factor-induced apoptosis of gastric cancer cells.6
336757842021ADAM28 from both endothelium and gastric cancer cleaves von Willebrand Factor to eliminate von Willebrand Factor-induced apoptosis of gastric cancer cells.6
328617072020ADAM28: Another ambivalent protease in cancer.6
335432122020[Construction of ADAM28 shRNA interference vector and its inhibitory effect on human periodontal ligament stem cells].0
328617072020ADAM28: Another ambivalent protease in cancer.6
335432122020[Construction of ADAM28 shRNA interference vector and its inhibitory effect on human periodontal ligament stem cells].0
304291062019ADAM28 promotes tumor growth and dissemination of acute myeloid leukemia through IGFBP-3 degradation and IGF-I-induced cell proliferation.5
316021602019Oncogenic ADAM28 induces gemcitabine resistance and predicts a poor prognosis in pancreatic cancer.13
304291062019ADAM28 promotes tumor growth and dissemination of acute myeloid leukemia through IGFBP-3 degradation and IGF-I-induced cell proliferation.5
316021602019Oncogenic ADAM28 induces gemcitabine resistance and predicts a poor prognosis in pancreatic cancer.13
286239762017ADAM28 localizes to HLA-G(+) trophoblasts and promotes column cell outgrowth.3
292542952017Serum levels of ADAM10, ADAM12, ADAM17 AND ADAM28 in colorectal cancer patients.9
286239762017ADAM28 localizes to HLA-G(+) trophoblasts and promotes column cell outgrowth.3

Citation

Dessen P

ADAM28 (ADAM metallopeptidase domain 28)

Atlas Genet Cytogenet Oncol Haematol. 2012-12-01

Online version: http://atlasgeneticsoncology.org/gene/53088/adam28-(adam-metallopeptidase-domain-28)