Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, contribute in submission tool
Other Information
Locus ID:
NCBI: 9447
MIM: 604578
HGNC: 357
Ensembl: ENSG00000163568
Variants:
dbSNP: 9447
ClinVar: 9447
TCGA: ENSG00000163568
COSMIC: AIM2
RNA/Proteins
| Gene ID | Transcript ID | Uniprot |
|---|---|---|
| ENSG00000163568 | ENST00000368129 | Q5T3W0 |
| ENSG00000163568 | ENST00000368130 | O14862 |
Expression (GTEx)
Pathways
Protein levels (Protein atlas)
References
| Pubmed ID | Year | Title | Citations |
|---|---|---|---|
| 37480196 | 2024 | Association of salivary levels of DNA sensing inflammasomes AIM2, IFI16, and cytokine IL18 with periodontitis and diabetes. | 0 |
| 38078661 | 2024 | AIM2 participates in house dust mite (HDM)-induced epithelial dysfunctions and ovalbumin (OVA)-induced allergic asthma in infant mice. | 0 |
| 38142900 | 2024 | AIM2 inflammasome: A potential therapeutic target in ischemic stroke. | 2 |
| 38166970 | 2024 | AIM2 promotes irradiation resistance, migration ability and PD-L1 expression through STAT1/NF-κB activation in oral squamous cell carcinoma. | 1 |
| 38251918 | 2024 | Cutting Edge: Cytosolic Receptor AIM2 Is Induced by Peroxisome Proliferator-activated Receptor γ following Mycobacterium tuberculosis Infection of Human Macrophages but Does Not Contribute to IL-1β Release. | 1 |
| 38594840 | 2024 | Cytosolic DNA sensor AIM2 promotes KRAS-driven lung cancer independent of inflammasomes. | 1 |
| 38731826 | 2024 | Herpes Simplex Virus ICP27 Protein Inhibits AIM 2-Dependent Inflammasome Influencing Pro-Inflammatory Cytokines Release in Human Pigment Epithelial Cells (hTert-RPE 1). | 0 |
| 38734775 | 2024 | Inflammatory corpuscle AIM2 facilitates macrophage foam cell formation by inhibiting cholesterol efflux protein ABCA1. | 0 |
| 38869352 | 2024 | AIM2 inflammasome regulated by the IFN-γ/JAK2/STAT1 pathway promotes activation and pyroptosis of monocytes in Coronary Artery Disease. | 0 |
| 37480196 | 2024 | Association of salivary levels of DNA sensing inflammasomes AIM2, IFI16, and cytokine IL18 with periodontitis and diabetes. | 0 |
| 38078661 | 2024 | AIM2 participates in house dust mite (HDM)-induced epithelial dysfunctions and ovalbumin (OVA)-induced allergic asthma in infant mice. | 0 |
| 38142900 | 2024 | AIM2 inflammasome: A potential therapeutic target in ischemic stroke. | 2 |
| 38166970 | 2024 | AIM2 promotes irradiation resistance, migration ability and PD-L1 expression through STAT1/NF-κB activation in oral squamous cell carcinoma. | 1 |
| 38251918 | 2024 | Cutting Edge: Cytosolic Receptor AIM2 Is Induced by Peroxisome Proliferator-activated Receptor γ following Mycobacterium tuberculosis Infection of Human Macrophages but Does Not Contribute to IL-1β Release. | 1 |
| 38594840 | 2024 | Cytosolic DNA sensor AIM2 promotes KRAS-driven lung cancer independent of inflammasomes. | 1 |
Citation
Dessen P
AIM2 (absent in melanoma 2)
Atlas Genet Cytogenet Oncol Haematol. 2012-12-01
Online version: http://atlasgeneticsoncology.org/gene/53092/aim2-(absent-in-melanoma-2)
