Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, contribute in submission tool
Other Information
Locus ID:
NCBI: 79879
MIM: 618788
HGNC: 26185
Ensembl: ENSG00000100147
Variants:
dbSNP: 79879
ClinVar: 79879
TCGA: ENSG00000100147
COSMIC: CCDC134
RNA/Proteins
| Gene ID | Transcript ID | Uniprot |
|---|---|---|
| ENSG00000100147 | ENST00000255784 | Q9H6E4 |
| ENSG00000100147 | ENST00000402061 | B0QY51 |
Expression (GTEx)
Protein levels (Protein atlas)
References
| Pubmed ID | Year | Title | Citations |
|---|---|---|---|
| 36056852 | 2023 | miRNA-1260b Promotes Breast Cancer Cell Migration and Invasion by Downregulating CCDC134. | 4 |
| 36056852 | 2023 | miRNA-1260b Promotes Breast Cancer Cell Migration and Invasion by Downregulating CCDC134. | 4 |
| 34382738 | 2021 | Ccdc134 deficiency impairs cerebellar development and motor coordination. | 0 |
| 34382738 | 2021 | Ccdc134 deficiency impairs cerebellar development and motor coordination. | 0 |
| 32181939 | 2020 | Homozygous Loss-of-Function Mutations in CCDC134 Are Responsible for a Severe Form of Osteogenesis Imperfecta. | 20 |
| 32181939 | 2020 | Homozygous Loss-of-Function Mutations in CCDC134 Are Responsible for a Severe Form of Osteogenesis Imperfecta. | 20 |
| 29115376 | 2018 | CCDC134 serves a crucial role in embryonic development. | 5 |
| 29115376 | 2018 | CCDC134 serves a crucial role in embryonic development. | 5 |
| 25125657 | 2014 | Cytokine-like molecule CCDC134 contributes to CD8⁺ T-cell effector functions in cancer immunotherapy. | 8 |
| 25125657 | 2014 | Cytokine-like molecule CCDC134 contributes to CD8⁺ T-cell effector functions in cancer immunotherapy. | 8 |
| 23070808 | 2013 | CCDC134 is down-regulated in gastric cancer and its silencing promotes cell migration and invasion of GES-1 and AGS cells via the MAPK pathway. | 16 |
| 23070808 | 2013 | CCDC134 is down-regulated in gastric cancer and its silencing promotes cell migration and invasion of GES-1 and AGS cells via the MAPK pathway. | 16 |
| 22644376 | 2012 | CCDC134 interacts with hADA2a and functions as a regulator of hADA2a in acetyltransferase activity, DNA damage-induced apoptosis and cell cycle arrest. | 8 |
| 22644376 | 2012 | CCDC134 interacts with hADA2a and functions as a regulator of hADA2a in acetyltransferase activity, DNA damage-induced apoptosis and cell cycle arrest. | 8 |
| 18087676 | 2008 | CCDC134, a novel secretory protein, inhibits activation of ERK and JNK, but not p38 MAPK. | 8 |
Citation
Dessen P
CCDC134 (coiled-coil domain containing 134)
Atlas Genet Cytogenet Oncol Haematol. 2012-12-01
Online version: http://atlasgeneticsoncology.org/gene/53097/ccdc134-(coiled-coil-domain-containing-134)
