Identity
HGNC
LOCATION
11p11.2
LOCUSID
ALIAS
ABH3,DEPC-1,DEPC1,PCA1,hABH3
FUSION GENES
Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, contribute in submission tool
Other Information
Locus ID:
NCBI: 221120
MIM: 610603
HGNC: 30141
Ensembl: ENSG00000166199
Variants:
dbSNP: 221120
ClinVar: 221120
TCGA: ENSG00000166199
COSMIC: ALKBH3
RNA/Proteins
Expression (GTEx)
Pathways
Protein levels (Protein atlas)
References
| Pubmed ID | Year | Title | Citations |
|---|---|---|---|
| 38118002 | 2024 | Histone lactylation-boosted ALKBH3 potentiates tumor progression and diminished promyelocytic leukemia protein nuclear condensates by m1A demethylation of SP100A. | 2 |
| 38158383 | 2024 | The Molecular Basis of Human ALKBH3 Mediated RNA N(1) -methyladenosine (m(1) A) Demethylation. | 1 |
| 38256217 | 2024 | The Role of Key Amino Acids of the Human Fe(II)/2OG-Dependent Dioxygenase ALKBH3 in Structural Dynamics and Repair Activity toward Methylated DNA. | 0 |
| 38118002 | 2024 | Histone lactylation-boosted ALKBH3 potentiates tumor progression and diminished promyelocytic leukemia protein nuclear condensates by m1A demethylation of SP100A. | 2 |
| 38158383 | 2024 | The Molecular Basis of Human ALKBH3 Mediated RNA N(1) -methyladenosine (m(1) A) Demethylation. | 1 |
| 38256217 | 2024 | The Role of Key Amino Acids of the Human Fe(II)/2OG-Dependent Dioxygenase ALKBH3 in Structural Dynamics and Repair Activity toward Methylated DNA. | 0 |
| 36098205 | 2022 | LncRNA ALKBH3-AS1 enhances ALKBH3 mRNA stability to promote hepatocellular carcinoma cell proliferation and invasion. | 5 |
| 36098205 | 2022 | LncRNA ALKBH3-AS1 enhances ALKBH3 mRNA stability to promote hepatocellular carcinoma cell proliferation and invasion. | 5 |
| 32915956 | 2021 | Epigenetic loss of m1A RNA demethylase ALKBH3 in Hodgkin lymphoma targets collagen, conferring poor clinical outcome. | 22 |
| 34081827 | 2021 | Programmable RNA N(1) -Methyladenosine Demethylation by a Cas13d-Directed Demethylase. | 14 |
| 34217309 | 2021 | ALKBH3 partner ASCC3 mediates P-body formation and selective clearance of MMS-induced 1-methyladenosine and 3-methylcytosine from mRNA. | 10 |
| 32915956 | 2021 | Epigenetic loss of m1A RNA demethylase ALKBH3 in Hodgkin lymphoma targets collagen, conferring poor clinical outcome. | 22 |
| 34081827 | 2021 | Programmable RNA N(1) -Methyladenosine Demethylation by a Cas13d-Directed Demethylase. | 14 |
| 34217309 | 2021 | ALKBH3 partner ASCC3 mediates P-body formation and selective clearance of MMS-induced 1-methyladenosine and 3-methylcytosine from mRNA. | 10 |
| 30342176 | 2019 | Human ALKBH3-induced m(1)A demethylation increases the CSF-1 mRNA stability in breast and ovarian cancer cells. | 69 |
Citation
Dessen P
ALKBH3 (alkB homolog 3, alpha-ketoglutarate dependent dioxygenase)
Atlas Genet Cytogenet Oncol Haematol. 2012-12-01
Online version: http://atlasgeneticsoncology.org/gene/53106/alkbh3-(alkb-homolog-3-alpha-ketoglutarate-dependent-dioxygenase)
