FAM83B (family with sequence similarity 83 member B)

2012-12-01   Dessen P  

Identity

HGNC
FAM83B
LOCATION
6p12.1
LOCUSID
222584
ALIAS
C6orf143
FUSION GENES
Show Gene Fusions

Other Information

Locus ID:

NCBI: 222584
HGNC: 21357
Ensembl: ENSG00000168143

Variants:

dbSNP: 222584
ClinVar: 222584
TCGA: ENSG00000168143
COSMIC: FAM83B

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000168143ENST00000306858Q5T0W9

Expression (GTEx)

0
5
10
15
20
25
30
35
40
45
Adipose - Subcutaneous
Adipose - Visceral
Adrenal Gland
Artery - Aorta
Artery - Tibial
Bladder
Brain - Amygdala
Brain - Anterior cingulate cortex
Brain - Caudate
Brain - Cerebellar Hemisphere
Brain - Cerebellum
Brain - Cortex
Brain - Frontal Cortex
Brain - Hippocampus
Brain - Hypothalamus
Brain - Nucleus accumbens
Brain - Putamen
Brain - Spinal cord
Brain - Substantia nigra
Breast - Mammary Tissue
Cells - Cultured fibroblasts
Cells - EBV - transformed lymphocytes
Cervix - Ectocervix
Cervix - Endocervix
Colon - Sigmoid
Colon - Transverse
Esophagus - Gastroesophageal Junction
Esophagus - Mucosa
Esophagus - Muscularis
Fallopian Tube
Heart - Atrial Appendage
Heart - Left Ventricle
Kidney - Cortex
Kidney - Medulla
Liver
Lung
Minor Salivary Gland
Muscle - Skeletal
Nerve - Tibial
Ovary
Pancreas
Pituitary
Prostate
Skin - Not Sun Exposed
Skin - Sun Exposed
Small Intestine - Terminal Ileum
Spleen
Stomach
Testis
Thyroid
Uterus
Vagina
Whole Blood

Protein levels (Protein atlas)

Not detected
Low
Medium
High
cerebral cortex
cerebellum
hippocampus
caudate
thyroid gland
parathyroid gland
adrenal gland
nasopharynx
bronchus
lung
oral mucosa
salivary gland
esophagus
stomach 1
stomach 2
duodenum
small intestine
colon
rectum
liver
gallbladder
pancreas
kidney
urinary bladder
testis
epididymis
seminal vesicle
prostate
vagina
ovary
fallopian tube
endometrium 1
endometrium 2
cervix, uterine
placenta
breast
heart muscle
smooth muscle
skeletal muscle
soft tissue 1
soft tissue 2
adipose tissue
skin 1
skin 2
appendix
spleen
lymph node
tonsil
bone marrow

References

Pubmed IDYearTitleCitations
384781702024FAM83B regulates mitochondrial metabolism and anti-apoptotic activity in pulmonary adenocarcinoma.0
384781702024FAM83B regulates mitochondrial metabolism and anti-apoptotic activity in pulmonary adenocarcinoma.0
366909872023FAM83B promotes the invasion of primary lung adenocarcinoma via PI3K/AKT/NF-κB pathway.3
366909872023FAM83B promotes the invasion of primary lung adenocarcinoma via PI3K/AKT/NF-κB pathway.3
355978452022FAM83B is involved in thyroid cancer cell differentiation and migration.3
355978452022FAM83B is involved in thyroid cancer cell differentiation and migration.3
336498012021MicroRNA‑199a/b‑5p inhibits endometrial cancer cell metastasis and invasion by targeting FAM83B in the epithelial‑to‑mesenchymal transition signaling pathway.5
336498012021MicroRNA‑199a/b‑5p inhibits endometrial cancer cell metastasis and invasion by targeting FAM83B in the epithelial‑to‑mesenchymal transition signaling pathway.5
255860592015FAM83B is a novel biomarker for diagnosis and prognosis of lung squamous cell carcinoma.26
255860592015FAM83B is a novel biomarker for diagnosis and prognosis of lung squamous cell carcinoma.26
239124602014Hyperactivation of EGFR and downstream effector phospholipase D1 by oncogenic FAM83B.26
239124602014Hyperactivation of EGFR and downstream effector phospholipase D1 by oncogenic FAM83B.26
236764672013FAM83B-mediated activation of PI3K/AKT and MAPK signaling cooperates to promote epithelial cell transformation and resistance to targeted therapies.38
236764672013FAM83B-mediated activation of PI3K/AKT and MAPK signaling cooperates to promote epithelial cell transformation and resistance to targeted therapies.38
228863022012FAM83B mediates EGFR- and RAS-driven oncogenic transformation.69

Citation

Dessen P

FAM83B (family with sequence similarity 83 member B)

Atlas Genet Cytogenet Oncol Haematol. 2012-12-01

Online version: http://atlasgeneticsoncology.org/gene/53113/fam83b-(family-with-sequence-similarity-83-member-b)