LDAH (lipid droplet associated hydrolase)

2013-01-01  

Identity

HGNC
LDAH
LOCATION
2p24.1
LOCUSID
60526
ALIAS
C2orf43,hLDAH
FUSION GENES
Show Gene Fusions

Other Information

Locus ID:

NCBI: 60526
MIM: 613570
HGNC: 26145
Ensembl: ENSG00000118961

Variants:

dbSNP: 60526
ClinVar: 60526
TCGA: ENSG00000118961
COSMIC: LDAH

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000118961ENST00000237822Q9H6V9
ENSG00000118961ENST00000381090B5MDU6
ENSG00000118961ENST00000402479B5MCE2
ENSG00000118961ENST00000403006B5MCU4
ENSG00000118961ENST00000412261C9JUM0
ENSG00000118961ENST00000419825D3YTH1
ENSG00000118961ENST00000432947C9JHU6
ENSG00000118961ENST00000435420A0A0A0MSH6
ENSG00000118961ENST00000440866B4DRG3
ENSG00000118961ENST00000541941Q9H6V9
ENSG00000118961ENST00000619656Q9H6V9
ENSG00000118961ENST00000626491Q9H6V9

Expression (GTEx)

0
5
10
15
20
25
Adipose - Subcutaneous
Adipose - Visceral
Adrenal Gland
Artery - Aorta
Artery - Tibial
Bladder
Brain - Amygdala
Brain - Anterior cingulate cortex
Brain - Caudate
Brain - Cerebellar Hemisphere
Brain - Cerebellum
Brain - Cortex
Brain - Frontal Cortex
Brain - Hippocampus
Brain - Hypothalamus
Brain - Nucleus accumbens
Brain - Putamen
Brain - Spinal cord
Brain - Substantia nigra
Breast - Mammary Tissue
Cells - Cultured fibroblasts
Cells - EBV - transformed lymphocytes
Cervix - Ectocervix
Cervix - Endocervix
Colon - Sigmoid
Colon - Transverse
Esophagus - Gastroesophageal Junction
Esophagus - Mucosa
Esophagus - Muscularis
Fallopian Tube
Heart - Atrial Appendage
Heart - Left Ventricle
Kidney - Cortex
Kidney - Medulla
Liver
Lung
Minor Salivary Gland
Muscle - Skeletal
Nerve - Tibial
Ovary
Pancreas
Pituitary
Prostate
Skin - Not Sun Exposed
Skin - Sun Exposed
Small Intestine - Terminal Ileum
Spleen
Stomach
Testis
Thyroid
Uterus
Vagina
Whole Blood

Protein levels (Protein atlas)

Not detected
Low
Medium
High
cerebral cortex
cerebellum
hippocampus
caudate
thyroid gland
parathyroid gland
adrenal gland
nasopharynx
bronchus
lung
oral mucosa
salivary gland
esophagus
stomach 1
stomach 2
duodenum
small intestine
colon
rectum
liver
gallbladder
pancreas
kidney
urinary bladder
testis
epididymis
seminal vesicle
prostate
vagina
ovary
fallopian tube
endometrium 1
endometrium 2
cervix, uterine
placenta
breast
heart muscle
smooth muscle
skeletal muscle
soft tissue 1
soft tissue 2
adipose tissue
skin 1
skin 2
appendix
spleen
lymph node
tonsil
bone marrow

References

Pubmed IDYearTitleCitations
301696302018Loss of LDAH associated with prostate cancer and hearing loss.9
301696302018Loss of LDAH associated with prostate cancer and hearing loss.9
243570602014Novel lipid droplet-associated serine hydrolase regulates macrophage cholesterol mobilization.26
243570602014Novel lipid droplet-associated serine hydrolase regulates macrophage cholesterol mobilization.26
226622422012Replication and fine mapping for association of the C2orf43, FOXP4, GPRC6A and RFX6 genes with prostate cancer in the Chinese population.22
226622422012Replication and fine mapping for association of the C2orf43, FOXP4, GPRC6A and RFX6 genes with prostate cancer in the Chinese population.22
203796142010Personalized smoking cessation: interactions between nicotine dose, dependence and quit-success genotype score.78
206760982010Genome-wide association study identifies five new susceptibility loci for prostate cancer in the Japanese population.154
203796142010Personalized smoking cessation: interactions between nicotine dose, dependence and quit-success genotype score.78
206760982010Genome-wide association study identifies five new susceptibility loci for prostate cancer in the Japanese population.154

Citation

Dessen P

LDAH (lipid droplet associated hydrolase)

Atlas Genet Cytogenet Oncol Haematol. 2013-01-01

Online version: http://atlasgeneticsoncology.org/gene/53125/ldah-(lipid-droplet-associated-hydrolase)