CDCA3 (cell division cycle associated 3)

2013-01-01  

Identity

HGNC
LOCATION
12p13.31
LOCUSID
ALIAS
GRCC8,TOME-1

Other Information

Locus ID:

NCBI: 83461
MIM: 607749
HGNC: 14624
Ensembl: ENSG00000111665

Variants:

dbSNP: 83461
ClinVar: 83461
TCGA: ENSG00000111665
COSMIC: CDCA3

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000111665ENST00000229265J3KMY0
ENSG00000111665ENST00000422785F8WDL1
ENSG00000111665ENST00000535406Q99618
ENSG00000111665ENST00000538862Q99618
ENSG00000111665ENST00000540683F5GX58

Expression (GTEx)

0
5
10
15
20
25
30

References

Pubmed IDYearTitleCitations
204160772010Identification of type 2 diabetes-associated combination of SNPs using support vector machine.26
252364632015Translating bioinformatics in oncology: guilt-by-profiling analysis and identification of KIF18B and CDCA3 as novel driver genes in carcinogenesis.23
228390992012Overexpression of cell cycle regulator CDCA3 promotes oral cancer progression by enhancing cell proliferation with prevention of G1 phase arrest.21
232198992013HoxB3 promotes prostate cancer cell progression by transactivating CDCA3.18
294396692018A novel miR-375-HOXB3-CDCA3/DNMT3B regulatory circuitry contributes to leukemogenesis in acute myeloid leukemia.10
157338612005Cell-cycle-dependent regulation of the human and mouse Tome-1 promoters.8
256731602015OY-TES-1 may regulate the malignant behavior of liver cancer via NANOG, CD9, CCND2 and CDCA3: a bioinformatic analysis combine with RNAi and oligonucleotide microarray.5
296275672018CDCA3 promotes cell proliferation by activating the NF-κB/cyclin D1 signaling pathway in colorectal cancer.3
302265752018CDCA3 mediates p21-dependent proliferation by regulating E2F1 expression in colorectal cancer.2
308164662019CDCA3 is a potential prognostic marker that promotes cell proliferation in gastric cancer.1

Citation

Dessen P

CDCA3 (cell division cycle associated 3)

Atlas Genet Cytogenet Oncol Haematol. 2013-01-01

Online version: http://atlasgeneticsoncology.org/gene/53126/cdca3-(cell-division-cycle-associated-3)