Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, contribute in submission tool
Other Information
Locus ID:
NCBI: 10941
MIM: 604716
HGNC: 12542
Ensembl: ENSG00000173610
Variants:
dbSNP: 10941
ClinVar: 10941
TCGA: ENSG00000173610
COSMIC: UGT2A1
RNA/Proteins
Expression (GTEx)
Pathways
Protein levels (Protein atlas)
PharmGKB
| Entity ID | Name | Type | Evidence | Association | PK | PD | PMIDs |
|---|---|---|---|---|---|---|---|
| PA10804 | imatinib | Chemical | ClinicalAnnotation | associated | PD | 30237583 | |
| PA151958383 | Gastrointestinal Stromal Tumors | Disease | ClinicalAnnotation | associated | PD | 30237583 |
References
| Pubmed ID | Year | Title | Citations |
|---|---|---|---|
| 35039640 | 2022 | The UGT2A1/UGT2A2 locus is associated with COVID-19-related loss of smell or taste. | 60 |
| 35039640 | 2022 | The UGT2A1/UGT2A2 locus is associated with COVID-19-related loss of smell or taste. | 60 |
| 30850392 | 2019 | Regulation of UGT2A1 by miR-196a-5p and miR-196b-5p. | 10 |
| 30850392 | 2019 | Regulation of UGT2A1 by miR-196a-5p and miR-196b-5p. | 10 |
| 29635252 | 2018 | Study of the Association of PEAR1, P2Y12, and UGT2A1 Polymorphisms with Platelet Reactivity in Response to Dual Antiplatelet Therapy in Chinese Patients. | 8 |
| 29635252 | 2018 | Study of the Association of PEAR1, P2Y12, and UGT2A1 Polymorphisms with Platelet Reactivity in Response to Dual Antiplatelet Therapy in Chinese Patients. | 8 |
| 23756265 | 2013 | The Human UDP-glucuronosyltransferase UGT2A1 and UGT2A2 enzymes are highly active in bile acid glucuronidation. | 19 |
| 23756265 | 2013 | The Human UDP-glucuronosyltransferase UGT2A1 and UGT2A2 enzymes are highly active in bile acid glucuronidation. | 19 |
| 22984225 | 2012 | Identification and functional characterization of a novel UDP-glucuronosyltransferase 2A1 splice variant: potential importance in tobacco-related cancer susceptibility. | 9 |
| 22984225 | 2012 | Identification and functional characterization of a novel UDP-glucuronosyltransferase 2A1 splice variant: potential importance in tobacco-related cancer susceptibility. | 9 |
| 21164388 | 2011 | Characterization of UDP-glucuronosyltransferase 2A1 (UGT2A1) variants and their potential role in tobacco carcinogenesis. | 17 |
| 21164388 | 2011 | Characterization of UDP-glucuronosyltransferase 2A1 (UGT2A1) variants and their potential role in tobacco carcinogenesis. | 17 |
| 19343046 | 2009 | Association study between single-nucleotide polymorphisms in 199 drug-related genes and commonly measured quantitative traits of 752 healthy Japanese subjects. | 4 |
| 19858781 | 2009 | Human UDP-glucuronosyltransferase UGT2A2: cDNA construction, expression, and functional characterization in comparison with UGT2A1 and UGT2A3. | 20 |
| 19898482 | 2009 | Genetic variants in TPMT and COMT are associated with hearing loss in children receiving cisplatin chemotherapy. | 105 |
Citation
Dessen P
UGT2A1 (UDP glucuronosyltransferase family 2 member A1 complex locus)
Atlas Genet Cytogenet Oncol Haematol. 2013-02-01
Online version: http://atlasgeneticsoncology.org/gene/53170/ugt2a1-(udp-glucuronosyltransferase-family-2-member-a1-complex-locus)
