Identity
HGNC
LOCATION
6p21.33
LOCUSID
ALIAS
BAT2,D6S51,D6S51E,G2
FUSION GENES
Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, contribute in submission tool
Other Information
Locus ID:
NCBI: 7916
MIM: 142580
HGNC: 13918
Ensembl: ENSG00000204469
Variants:
dbSNP: 7916
ClinVar: 7916
TCGA: ENSG00000204469
COSMIC: PRRC2A
RNA/Proteins
| Gene ID | Transcript ID | Uniprot |
|---|---|---|
| ENSG00000204469 | ENST00000376007 | P48634 |
| ENSG00000204469 | ENST00000376007 | A0A1U9X974 |
| ENSG00000204469 | ENST00000376033 | P48634 |
| ENSG00000204469 | ENST00000376033 | A0A1U9X974 |
Expression (GTEx)
Protein levels (Protein atlas)
PharmGKB
| Entity ID | Name | Type | Evidence | Association | PK | PD | PMIDs |
|---|---|---|---|---|---|---|---|
| PA443622 | Carcinoma, Non-Small-Cell Lung | Disease | ClinicalAnnotation | associated | PD | 31616045 | |
| PA445846 | Thrombocytopenia | Disease | ClinicalAnnotation | associated | PD | 31616045 | |
| PA448785 | carbamazepine | Chemical | ClinicalAnnotation | associated | PD | 16538176 | |
| PA448803 | carboplatin | Chemical | ClinicalAnnotation | associated | PD | 31616045 | |
| PA449748 | gemcitabine | Chemical | ClinicalAnnotation | associated | PD | 31616045 |
References
| Pubmed ID | Year | Title | Citations |
|---|---|---|---|
| 36964127 | 2023 | The m6A reader PRRC2A is essential for meiosis I completion during spermatogenesis. | 9 |
| 36964127 | 2023 | The m6A reader PRRC2A is essential for meiosis I completion during spermatogenesis. | 9 |
| 32862241 | 2021 | Common genetic variants in PRRC2A are associated with both neuromyelitis optica spectrum disorder and multiple sclerosis in Han Chinese population. | 5 |
| 32862241 | 2021 | Common genetic variants in PRRC2A are associated with both neuromyelitis optica spectrum disorder and multiple sclerosis in Han Chinese population. | 5 |
| 25111513 | 2014 | BAT2 and BAT3 polymorphisms as novel genetic risk factors for rejection after HLA-related SCT. | 3 |
| 25111513 | 2014 | BAT2 and BAT3 polymorphisms as novel genetic risk factors for rejection after HLA-related SCT. | 3 |
| 23121087 | 2013 | Sex-dependent associations of genetic variants identified by GWAS with indices of adiposity and obesity risk in a Chinese children population. | 12 |
| 23221128 | 2013 | Fine-mapping of the 5p15.33, 6p22.1-p21.31, and 15q25.1 regions identifies functional and histology-specific lung cancer susceptibility loci in African-Americans. | 20 |
| 23121087 | 2013 | Sex-dependent associations of genetic variants identified by GWAS with indices of adiposity and obesity risk in a Chinese children population. | 12 |
| 23221128 | 2013 | Fine-mapping of the 5p15.33, 6p22.1-p21.31, and 15q25.1 regions identifies functional and histology-specific lung cancer susceptibility loci in African-Americans. | 20 |
| 23047821 | 2012 | PRRC2A and BCL2L11 gene variants influence risk of non-Hodgkin lymphoma: results from the InterLymph consortium. | 26 |
| 23079975 | 2012 | Association of MHC class-III gene polymorphisms with ER-positive breast cancer in Chinese Han population. | 10 |
| 23047821 | 2012 | PRRC2A and BCL2L11 gene variants influence risk of non-Hodgkin lymphoma: results from the InterLymph consortium. | 26 |
| 23079975 | 2012 | Association of MHC class-III gene polymorphisms with ER-positive breast cancer in Chinese Han population. | 10 |
| 20098615 | 2010 | Application of gene network analysis techniques identifies AXIN1/PDIA2 and endoglin haplotypes associated with bicuspid aortic valve. | 28 |
Citation
Dessen P
PRRC2A (proline rich coiled-coil 2A)
Atlas Genet Cytogenet Oncol Haematol. 2013-02-01
Online version: http://atlasgeneticsoncology.org/gene/53192/prrc2a-(proline-rich-coiled-coil-2a)
