Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, contribute in submission tool
Other Information
Locus ID:
NCBI: 13
MIM: 600338
HGNC: 17
Ensembl: ENSG00000114771
Variants:
dbSNP: 13
ClinVar: 13
TCGA: ENSG00000114771
COSMIC: AADAC
RNA/Proteins
| Gene ID | Transcript ID | Uniprot |
|---|---|---|
| ENSG00000114771 | ENST00000232892 | P22760 |
| ENSG00000114771 | ENST00000488869 | C9K0E9 |
Expression (GTEx)
Pathways
| Pathway | Source | External ID |
|---|---|---|
| Metabolism | REACTOME | R-HSA-1430728 |
| Biological oxidations | REACTOME | R-HSA-211859 |
| Phase 1 - Functionalization of compounds | REACTOME | R-HSA-211945 |
Protein levels (Protein atlas)
References
| Pubmed ID | Year | Title | Citations |
|---|---|---|---|
| 37002641 | 2023 | In vitro deacetylation of N-acetylserotonin by arylacetamide deacetylase. | 0 |
| 37002641 | 2023 | In vitro deacetylation of N-acetylserotonin by arylacetamide deacetylase. | 0 |
| 35451495 | 2022 | AADAC promotes therapeutic activity of cisplatin and imatinib against ovarian cancer cells. | 2 |
| 35681154 | 2022 | Impact of AADAC gene expression on prognosis in patients with Borrmann type III advanced gastric cancer. | 4 |
| 35451495 | 2022 | AADAC promotes therapeutic activity of cisplatin and imatinib against ovarian cancer cells. | 2 |
| 35681154 | 2022 | Impact of AADAC gene expression on prognosis in patients with Borrmann type III advanced gastric cancer. | 4 |
| 34450168 | 2021 | Arylacetamide deacetylase as a determinant of the hydrolysis and activation of abiraterone acetate in mice and humans. | 2 |
| 34510815 | 2021 | Allelic and genotypic frequencies of NAT2, CYP2E1, and AADAC genes in a cohort of Peruvian tuberculosis patients. | 6 |
| 34450168 | 2021 | Arylacetamide deacetylase as a determinant of the hydrolysis and activation of abiraterone acetate in mice and humans. | 2 |
| 34510815 | 2021 | Allelic and genotypic frequencies of NAT2, CYP2E1, and AADAC genes in a cohort of Peruvian tuberculosis patients. | 6 |
| 30670438 | 2019 | A Population Pharmacokinetic Analysis Shows that Arylacetamide Deacetylase (AADAC) Gene Polymorphism and HIV Infection Affect the Exposure of Rifapentine. | 13 |
| 31235486 | 2019 | Arylacetamide Deacetylase Enzyme: Presence and Interindividual Variability in Human Lungs. | 1 |
| 30670438 | 2019 | A Population Pharmacokinetic Analysis Shows that Arylacetamide Deacetylase (AADAC) Gene Polymorphism and HIV Infection Affect the Exposure of Rifapentine. | 13 |
| 31235486 | 2019 | Arylacetamide Deacetylase Enzyme: Presence and Interindividual Variability in Human Lungs. | 1 |
| 29253601 | 2018 | Association of the AADAC gene and Tourette syndrome in a Han Chinese cohort. | 7 |
Citation
Dessen P
AADAC (arylacetamide deacetylase)
Atlas Genet Cytogenet Oncol Haematol. 2003-06-01
Online version: http://atlasgeneticsoncology.org/gene/532/aadac
