GMCL1 (germ cell-less 1, spermatogenesis associated)

2013-03-01  

Identity

HGNC
GMCL1
LOCATION
2p13.3
LOCUSID
64395
ALIAS
BTBD13,GCL,GCL1,SPATA29
FUSION GENES
Show Gene Fusions

Other Information

Locus ID:

NCBI: 64395
MIM: 618627
HGNC: 23843
Ensembl: ENSG00000087338

Variants:

dbSNP: 64395
ClinVar: 64395
TCGA: ENSG00000087338
COSMIC: GMCL1

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000087338ENST00000282570Q96IK5
ENSG00000087338ENST00000282570Q53SE7

Expression (GTEx)

0
5
10
15
20
25
Adipose - Subcutaneous
Adipose - Visceral
Adrenal Gland
Artery - Aorta
Artery - Tibial
Bladder
Brain - Amygdala
Brain - Anterior cingulate cortex
Brain - Caudate
Brain - Cerebellar Hemisphere
Brain - Cerebellum
Brain - Cortex
Brain - Frontal Cortex
Brain - Hippocampus
Brain - Hypothalamus
Brain - Nucleus accumbens
Brain - Putamen
Brain - Spinal cord
Brain - Substantia nigra
Breast - Mammary Tissue
Cells - Cultured fibroblasts
Cells - EBV - transformed lymphocytes
Cervix - Ectocervix
Cervix - Endocervix
Colon - Sigmoid
Colon - Transverse
Esophagus - Gastroesophageal Junction
Esophagus - Mucosa
Esophagus - Muscularis
Fallopian Tube
Heart - Atrial Appendage
Heart - Left Ventricle
Kidney - Cortex
Kidney - Medulla
Liver
Lung
Minor Salivary Gland
Muscle - Skeletal
Nerve - Tibial
Ovary
Pancreas
Pituitary
Prostate
Skin - Not Sun Exposed
Skin - Sun Exposed
Small Intestine - Terminal Ileum
Spleen
Stomach
Testis
Thyroid
Uterus
Vagina
Whole Blood

Protein levels (Protein atlas)

Not detected
Low
Medium
High
cerebral cortex
cerebellum
hippocampus
caudate
thyroid gland
parathyroid gland
adrenal gland
nasopharynx
bronchus
lung
oral mucosa
salivary gland
esophagus
stomach 1
stomach 2
duodenum
small intestine
colon
rectum
liver
gallbladder
pancreas
kidney
urinary bladder
testis
epididymis
seminal vesicle
prostate
vagina
ovary
fallopian tube
endometrium 1
endometrium 2
cervix, uterine
placenta
breast
heart muscle
smooth muscle
skeletal muscle
soft tissue 1
soft tissue 2
adipose tissue
skin 1
skin 2
appendix
spleen
lymph node
tonsil
bone marrow

References

Pubmed IDYearTitleCitations
124937652003Transcriptional repressor germ cell-less (GCL) and barrier to autointegration factor (BAF) compete for binding to emerin in vitro.76
98780641999Integration of a growth-suppressing BTB/POZ domain protein with the DP component of the E2F transcription factor.19
129546562003Reduced human germ cell-less (HGCL) expression in azoospermic men with severe germinal cell impairment.5
230292592012GAGE cancer-germline antigens are recruited to the nuclear envelope by germ cell-less (GCL).5
129278082003Enhanced degradation of MDM2 by a nuclear envelope component, mouse germ cell-less.3

Citation

Dessen P

GMCL1 (germ cell-less 1, spermatogenesis associated)

Atlas Genet Cytogenet Oncol Haematol. 2013-03-01

Online version: http://atlasgeneticsoncology.org/gene/53214/gmcl1-(germ-cell-less-1-spermatogenesis-associated)