CYTIP (cytohesin 1 interacting protein)

2013-03-01  

Identity

HGNC
LOCATION
2q24.1
LOCUSID
ALIAS
B3-1,CASP,CYBR,CYTHIP,HE,PSCDBP
FUSION GENES

Other Information

Locus ID:

NCBI: 9595
MIM: 604448
HGNC: 9506
Ensembl: ENSG00000115165

Variants:

dbSNP: 9595
ClinVar: 9595
TCGA: ENSG00000115165
COSMIC: CYTIP

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000115165ENST00000264192O60759
ENSG00000115165ENST00000418920C9JSM2
ENSG00000115165ENST00000435117C9JNN8
ENSG00000115165ENST00000439355C9JRF8
ENSG00000115165ENST00000457793F8WF61

Expression (GTEx)

0
50
100
150
200

Protein levels (Protein atlas)

Not detected
Low
Medium
High

References

Pubmed IDYearTitleCitations
232230052013Epigenetic expansion of VHL-HIF signal output drives multiorgan metastasis in renal cancer.81
203796142010Personalized smoking cessation: interactions between nicotine dose, dependence and quit-success genotype score.62
120528272002The N-terminal coiled coil domain of the cytohesin/ARNO family of guanine nucleotide exchange factors interacts with the scaffolding protein CASP.20
175775832007Sorting nexin 27 interacts with the Cytohesin associated scaffolding protein (CASP) in lymphocytes.13
215620432011Infection of dendritic cells with herpes simplex virus type 1 induces rapid degradation of CYTIP, thereby modulating adhesion and migration.13
167022242006Cytohesin binder and regulator augments T cell receptor-induced nuclear factor of activated T Cells.AP-1 activation through regulation of the JNK pathway.5
250584602014Cytohesin-associated scaffolding protein (CASP) is involved in migration and IFN-γ secretion in natural killer cells.1
234690182013In human monocyte derived dendritic cells SOCS1 interacting with CYTIP induces the degradation of CYTIP by the proteasome.0

Citation

Dessen P

CYTIP (cytohesin 1 interacting protein)

Atlas Genet Cytogenet Oncol Haematol. 2013-03-01

Online version: http://atlasgeneticsoncology.org/gene/53225/cytip-(cytohesin-1-interacting-protein)