JMJD6 (jumonji domain containing 6, arginine demethylase and lysine hydroxylase)
2013-03-01 AffiliationIdentity
HGNC
LOCATION
17q25.1
LOCUSID
ALIAS
PSR,PTDSR,PTDSR1
FUSION GENES
Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, contribute in submission tool
Other Information
Locus ID:
NCBI: 23210
MIM: 604914
HGNC: 19355
Ensembl: ENSG00000070495
Variants:
dbSNP: 23210
ClinVar: 23210
TCGA: ENSG00000070495
COSMIC: JMJD6
RNA/Proteins
Expression (GTEx)
Pathways
| Pathway | Source | External ID |
|---|---|---|
| Chromatin organization | REACTOME | R-HSA-4839726 |
| Chromatin modifying enzymes | REACTOME | R-HSA-3247509 |
| HDMs demethylate histones | REACTOME | R-HSA-3214842 |
Protein levels (Protein atlas)
References
| Pubmed ID | Year | Title | Citations |
|---|---|---|---|
| 36683415 | 2023 | Fibronectin and JMJD6 Signature in Circulating Placental Extracellular Vesicles for the Detection of Preeclampsia. | 0 |
| 36867680 | 2023 | JMJD6 Shapes a Pro-tumor Microenvironment via ANXA1-Dependent Macrophage Polarization in Breast Cancer. | 3 |
| 37188718 | 2023 | Predictive network analysis identifies JMJD6 and other potential key drivers in Alzheimer's disease. | 3 |
| 37567973 | 2023 | JMJD6 in tumor-associated macrophage regulates macrophage polarization and cancer progression via STAT3/IL-10 axis. | 4 |
| 37880710 | 2023 | JMJD6-BRD4 complex stimulates lncRNA HOTAIR transcription by binding to the promoter region of HOTAIR and induces radioresistance in liver cancer stem cells. | 2 |
| 36683415 | 2023 | Fibronectin and JMJD6 Signature in Circulating Placental Extracellular Vesicles for the Detection of Preeclampsia. | 0 |
| 36867680 | 2023 | JMJD6 Shapes a Pro-tumor Microenvironment via ANXA1-Dependent Macrophage Polarization in Breast Cancer. | 3 |
| 37188718 | 2023 | Predictive network analysis identifies JMJD6 and other potential key drivers in Alzheimer's disease. | 3 |
| 37567973 | 2023 | JMJD6 in tumor-associated macrophage regulates macrophage polarization and cancer progression via STAT3/IL-10 axis. | 4 |
| 37880710 | 2023 | JMJD6-BRD4 complex stimulates lncRNA HOTAIR transcription by binding to the promoter region of HOTAIR and induces radioresistance in liver cancer stem cells. | 2 |
| 34875075 | 2022 | The Epigenetic Regulator Jumonji Domain-Containing Protein 6 (JMJD6) Is Highly Expressed but Not Prognostic in IDH-Wildtype Glioblastoma Patients. | 0 |
| 35359945 | 2022 | Role of the Epigenetic Modifier JMJD6 in Tumor Development and Regulation of Immune Response. | 8 |
| 35442509 | 2022 | MiR-298 suppresses the malignant progression of osteosarcoma by targeting JMJD6. | 1 |
| 35764091 | 2022 | An oncogenic JMJD6-DGAT1 axis tunes the epigenetic regulation of lipid droplet formation in clear cell renal cell carcinoma. | 10 |
| 35930668 | 2022 | Widespread hydroxylation of unstructured lysine-rich protein domains by JMJD6. | 10 |
Citation
Dessen P
JMJD6 (jumonji domain containing 6, arginine demethylase and lysine hydroxylase)
Atlas Genet Cytogenet Oncol Haematol. 2013-03-01
Online version: http://atlasgeneticsoncology.org/gene/53229/jmjd6-(jumonji-domain-containing-6-arginine-demethylase-and-lysine-hydroxylase)
