SEC14L1 (SEC14 like lipid binding 1)

2013-04-01  

Identity

HGNC
LOCATION
17q25.2
LOCUSID
ALIAS
PRELID4A,SEC14L
FUSION GENES

Other Information

Locus ID:

NCBI: 6397
MIM: 601504
HGNC: 10698
Ensembl: ENSG00000129657

Variants:

dbSNP: 6397
ClinVar: 6397
TCGA: ENSG00000129657
COSMIC: SEC14L1

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000129657ENST00000392476Q92503
ENSG00000129657ENST00000430767Q92503
ENSG00000129657ENST00000431431Q92503
ENSG00000129657ENST00000436233Q92503
ENSG00000129657ENST00000443798Q92503
ENSG00000129657ENST00000561721D5G3K4
ENSG00000129657ENST00000585618Q92503
ENSG00000129657ENST00000586429K7ELU0
ENSG00000129657ENST00000587820K7EQK4
ENSG00000129657ENST00000588488K7EIJ7
ENSG00000129657ENST00000588616K7ELM0
ENSG00000129657ENST00000588880K7EJJ2
ENSG00000129657ENST00000589202K7EPE4
ENSG00000129657ENST00000589827K7EJ08
ENSG00000129657ENST00000590483K7ESI4
ENSG00000129657ENST00000591437Q92503
ENSG00000129657ENST00000591786K7ERB3

Expression (GTEx)

0
10
20
30
40
50
60
70
80

Protein levels (Protein atlas)

Not detected
Low
Medium
High

References

Pubmed IDYearTitleCitations
230838322012A 12-gene expression signature is associated with aggressive histological in prostate cancer: SEC14L1 and TCEB1 genes are potential markers of progression.14
238436402013Negative regulation of RIG-I-mediated innate antiviral signaling by SEC14L1.10
223740942012Sec14 like PITPs couple lipid metabolism with phosphoinositide synthesis to regulate Golgi functionality.6
278551582016High-Resolution Genetics Identifies the Lipid Transfer Protein Sec14p as Target for Antifungal Ergolines.3
299551492018Saccharomyces cerevisiae-like 1 (SEC14L1) is a prognostic factor in breast cancer associated with lymphovascular invasion.3
257012282015Saccharomyces cerevisiae-like 1 overexpression is frequent in prostate cancer and has markedly different effects in Ets-related gene fusion-positive and fusion-negative cancers.2

Citation

Dessen P

SEC14L1 (SEC14 like lipid binding 1)

Atlas Genet Cytogenet Oncol Haematol. 2013-04-01

Online version: http://atlasgeneticsoncology.org/gene/53236/sec14l1-(sec14-like-lipid-binding-1)