Identity
HGNC
LOCATION
20q13.31
LOCUSID
ALIAS
C20orf32,CAS4,HEFL,HEPL
FUSION GENES
Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, contribute in submission tool
Other Information
Locus ID:
NCBI: 57091
MIM: 618888
HGNC: 15878
Ensembl: ENSG00000087589
Variants:
dbSNP: 57091
ClinVar: 57091
TCGA: ENSG00000087589
COSMIC: CASS4
RNA/Proteins
| Gene ID | Transcript ID | Uniprot |
|---|---|---|
| ENSG00000087589 | ENST00000360314 | Q9NQ75 |
| ENSG00000087589 | ENST00000434344 | Q9NQ75 |
Expression (GTEx)
Protein levels (Protein atlas)
References
| Pubmed ID | Year | Title | Citations |
|---|---|---|---|
| 29789968 | 2018 | Exploring the mechanistic insights of Cas scaffolding protein family member 4 with protein tyrosine kinase 2 in Alzheimer's disease by evaluating protein interactions through molecular docking and dynamic simulations. | 5 |
| 29789968 | 2018 | Exploring the mechanistic insights of Cas scaffolding protein family member 4 with protein tyrosine kinase 2 in Alzheimer's disease by evaluating protein interactions through molecular docking and dynamic simulations. | 5 |
| 27677288 | 2016 | Overexpression of CASS4 promotes invasion in non-small cell lung cancer by activating the AKT signaling pathway and inhibiting E-cadherin expression. | 5 |
| 27677288 | 2016 | Overexpression of CASS4 promotes invasion in non-small cell lung cancer by activating the AKT signaling pathway and inhibiting E-cadherin expression. | 5 |
| 26119091 | 2015 | Embryonal Fyn-associated substrate (EFS) and CASS4: The lesser-known CAS protein family members. | 13 |
| 26119091 | 2015 | Embryonal Fyn-associated substrate (EFS) and CASS4: The lesser-known CAS protein family members. | 13 |
| 23001926 | 2013 | Overexpression and cytoplasmic accumulation of Hepl is associated with clinicopathological parameters and poor prognosis in non-small cell lung cancer. | 3 |
| 23001926 | 2013 | Overexpression and cytoplasmic accumulation of Hepl is associated with clinicopathological parameters and poor prognosis in non-small cell lung cancer. | 3 |
| 18256281 | 2008 | A novel Cas family member, HEPL, regulates FAK and cell spreading. | 38 |
| 18256281 | 2008 | A novel Cas family member, HEPL, regulates FAK and cell spreading. | 38 |
Citation
Dessen P
CASS4 (Cas scaffold protein family member 4)
Atlas Genet Cytogenet Oncol Haematol. 2013-04-01
Online version: http://atlasgeneticsoncology.org/gene/53239/cass4-(cas-scaffold-protein-family-member-4)
