Identity
HGNC
LOCATION
17q21.32
LOCUSID
ALIAS
LCR-F1,NRF1,TCF11
FUSION GENES
Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, contribute in submission tool
Other Information
Locus ID:
NCBI: 4779
MIM: 163260
HGNC: 7781
Ensembl: ENSG00000082641
Variants:
dbSNP: 4779
ClinVar: 4779
TCGA: ENSG00000082641
COSMIC: NFE2L1
RNA/Proteins
Expression (GTEx)
Protein levels (Protein atlas)
References
| Pubmed ID | Year | Title | Citations |
|---|---|---|---|
| 37996059 | 2024 | Loss of Nrf1 rather than Nrf2 leads to inflammatory accumulation of lipids and reactive oxygen species in human hepatoma cells, which is alleviated by 2-bromopalmitate. | 1 |
| 38656405 | 2024 | Transcription factor Nrf1 regulates proteotoxic stress-induced autophagy. | 0 |
| 37996059 | 2024 | Loss of Nrf1 rather than Nrf2 leads to inflammatory accumulation of lipids and reactive oxygen species in human hepatoma cells, which is alleviated by 2-bromopalmitate. | 1 |
| 38656405 | 2024 | Transcription factor Nrf1 regulates proteotoxic stress-induced autophagy. | 0 |
| 37473701 | 2023 | Unravelling the role of NFE2L1 in stress responses and related diseases. | 3 |
| 37658135 | 2023 | The transcription factor NRF1 (NFE2L1) activates aggrephagy by inducing p62 and GABARAPL1 after proteasome inhibition to maintain proteostasis. | 4 |
| 37681897 | 2023 | Transcription Factor NFE2L1 Decreases in Glomerulonephropathies after Podocyte Damage. | 1 |
| 37739987 | 2023 | Evaluation of the NRF1-proteasome axis as a therapeutic target in breast cancer. | 1 |
| 37848756 | 2023 | NFE2L1 restrains ferroptosis by transcriptionally regulating HJURP and participates in the progress of oral squamous cell carcinoma. | 1 |
| 38011090 | 2023 | Nrf1 is not a direct target gene of SREBP1, albeit both are integrated into the rapamycin-responsive regulatory network in human hepatoma cells. | 0 |
| 37473701 | 2023 | Unravelling the role of NFE2L1 in stress responses and related diseases. | 3 |
| 37658135 | 2023 | The transcription factor NRF1 (NFE2L1) activates aggrephagy by inducing p62 and GABARAPL1 after proteasome inhibition to maintain proteostasis. | 4 |
| 37681897 | 2023 | Transcription Factor NFE2L1 Decreases in Glomerulonephropathies after Podocyte Damage. | 1 |
| 37739987 | 2023 | Evaluation of the NRF1-proteasome axis as a therapeutic target in breast cancer. | 1 |
| 37848756 | 2023 | NFE2L1 restrains ferroptosis by transcriptionally regulating HJURP and participates in the progress of oral squamous cell carcinoma. | 1 |
Citation
Dessen P
NFE2L1 (nuclear factor, erythroid 2 like 1)
Atlas Genet Cytogenet Oncol Haematol. 2013-04-01
Online version: http://atlasgeneticsoncology.org/gene/53247/nfe2l1-(nuclear-factor-erythroid-2-like-1)
