NFE2L1 (nuclear factor, erythroid 2 like 1)

2013-04-01  

Identity

HGNC
LOCATION
17q21.32
LOCUSID
ALIAS
LCR-F1,NRF1,TCF11
FUSION GENES

Other Information

Locus ID:

NCBI: 4779
MIM: 163260
HGNC: 7781
Ensembl: ENSG00000082641

Variants:

dbSNP: 4779
ClinVar: 4779
TCGA: ENSG00000082641
COSMIC: NFE2L1

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000082641ENST00000357480Q14494
ENSG00000082641ENST00000361665J9JIE5
ENSG00000082641ENST00000362042Q14494
ENSG00000082641ENST00000536222F5H1B7
ENSG00000082641ENST00000577411J3KSR3
ENSG00000082641ENST00000577431J3QQQ1
ENSG00000082641ENST00000579537J3KSE0
ENSG00000082641ENST00000579889A0A0G2JLG9
ENSG00000082641ENST00000580037J3QQH8
ENSG00000082641ENST00000580050J3QRG7
ENSG00000082641ENST00000581319J3KRF3
ENSG00000082641ENST00000582155B4DYE1
ENSG00000082641ENST00000583210J3QR31
ENSG00000082641ENST00000583378J3QKY3
ENSG00000082641ENST00000584137J3QLQ1
ENSG00000082641ENST00000584634J3KTG6
ENSG00000082641ENST00000585062J3QQY8
ENSG00000082641ENST00000585291Q14494

Expression (GTEx)

0
100
200
300
400
500
600
700

Protein levels (Protein atlas)

Not detected
Low
Medium
High

References

Pubmed IDYearTitleCitations
379960592024Loss of Nrf1 rather than Nrf2 leads to inflammatory accumulation of lipids and reactive oxygen species in human hepatoma cells, which is alleviated by 2-bromopalmitate.1
386564052024Transcription factor Nrf1 regulates proteotoxic stress-induced autophagy.0
379960592024Loss of Nrf1 rather than Nrf2 leads to inflammatory accumulation of lipids and reactive oxygen species in human hepatoma cells, which is alleviated by 2-bromopalmitate.1
386564052024Transcription factor Nrf1 regulates proteotoxic stress-induced autophagy.0
374737012023Unravelling the role of NFE2L1 in stress responses and related diseases.3
376581352023The transcription factor NRF1 (NFE2L1) activates aggrephagy by inducing p62 and GABARAPL1 after proteasome inhibition to maintain proteostasis.4
376818972023Transcription Factor NFE2L1 Decreases in Glomerulonephropathies after Podocyte Damage.1
377399872023Evaluation of the NRF1-proteasome axis as a therapeutic target in breast cancer.1
378487562023NFE2L1 restrains ferroptosis by transcriptionally regulating HJURP and participates in the progress of oral squamous cell carcinoma.1
380110902023Nrf1 is not a direct target gene of SREBP1, albeit both are integrated into the rapamycin-responsive regulatory network in human hepatoma cells.0
374737012023Unravelling the role of NFE2L1 in stress responses and related diseases.3
376581352023The transcription factor NRF1 (NFE2L1) activates aggrephagy by inducing p62 and GABARAPL1 after proteasome inhibition to maintain proteostasis.4
376818972023Transcription Factor NFE2L1 Decreases in Glomerulonephropathies after Podocyte Damage.1
377399872023Evaluation of the NRF1-proteasome axis as a therapeutic target in breast cancer.1
378487562023NFE2L1 restrains ferroptosis by transcriptionally regulating HJURP and participates in the progress of oral squamous cell carcinoma.1

Citation

Dessen P

NFE2L1 (nuclear factor, erythroid 2 like 1)

Atlas Genet Cytogenet Oncol Haematol. 2013-04-01

Online version: http://atlasgeneticsoncology.org/gene/53247/nfe2l1-(nuclear-factor-erythroid-2-like-1)