MT1X (metallothionein 1X)

2013-05-01  

Identity

HGNC
LOCATION
16q13
LOCUSID
ALIAS
MT-1l,MT1
FUSION GENES

Other Information

Locus ID:

NCBI: 4501
MIM: 156359
HGNC: 7405
Ensembl: ENSG00000187193

Variants:

dbSNP: 4501
ClinVar: 4501
TCGA: ENSG00000187193
COSMIC: MT1X

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000187193ENST00000394485P80297
ENSG00000187193ENST00000394485A0A140VJP8
ENSG00000187193ENST00000562939U3KQD7
ENSG00000187193ENST00000564974U3KQD7

Expression (GTEx)

0
500
1000
1500
2000

Pathways

PathwaySourceExternal ID
Mineral absorptionKEGGko04978
Mineral absorptionKEGGhsa04978
MetabolismREACTOMER-HSA-1430728
Response to metal ionsREACTOMER-HSA-5660526
Metallothioneins bind metalsREACTOMER-HSA-5661231

References

Pubmed IDYearTitleCitations
361493222022MT1X is an oncogene and indicates prognosis in ccRCC.2
361493222022MT1X is an oncogene and indicates prognosis in ccRCC.2
309320102019Metallothionein Genes are Highly Expressed in Malignant Astrocytomas and Associated with Patient Survival.12
309320102019Metallothionein Genes are Highly Expressed in Malignant Astrocytomas and Associated with Patient Survival.12
298734152018Metallothionein 1 family profiling identifies MT1X as a tumor suppressor involved in the progression and metastastatic capacity of hepatocellular carcinoma.20
298734152018Metallothionein 1 family profiling identifies MT1X as a tumor suppressor involved in the progression and metastastatic capacity of hepatocellular carcinoma.20
271070862016Expression of Metallothionein and Vascular Endothelial Growth Factor Isoforms in Breast Cancer Cells.4
277972282016Evaluation of MT1XT20 Single Quasi-Monomorphic Mononucleotide Marker for Characterizing Microsatellite Instability in Persian Lynch Syndrome Patients.2
271070862016Expression of Metallothionein and Vascular Endothelial Growth Factor Isoforms in Breast Cancer Cells.4
277972282016Evaluation of MT1XT20 Single Quasi-Monomorphic Mononucleotide Marker for Characterizing Microsatellite Instability in Persian Lynch Syndrome Patients.2
246908792014Identification and characterization of MT-1X as a novel FHL3-binding partner.3
246908792014Identification and characterization of MT-1X as a novel FHL3-binding partner.3
227801242013Genome-wide association study of a quantitative disordered gambling trait.26
227801242013Genome-wide association study of a quantitative disordered gambling trait.26
221089042012T([20]) repeat in the 3'-untranslated region of the MT1X gene: a marker with high sensitivity and specificity to detect microsatellite instability in colorectal cancer.5

Citation

Dessen P

MT1X (metallothionein 1X)

Atlas Genet Cytogenet Oncol Haematol. 2013-05-01

Online version: http://atlasgeneticsoncology.org/gene/53262/mt1x-(metallothionein-1x)