Identity
HGNC
LOCATION
3p21.1
LOCUSID
ALIAS
HEL-S-48,HEL107,SDDHD,TK,TKT1
FUSION GENES
Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, contribute in submission tool
Other Information
Locus ID:
NCBI: 7086
MIM: 606781
HGNC: 11834
Ensembl: ENSG00000163931
Variants:
dbSNP: 7086
ClinVar: 7086
TCGA: ENSG00000163931
COSMIC: TKT
RNA/Proteins
Expression (GTEx)
Pathways
Protein levels (Protein atlas)
References
| Pubmed ID | Year | Title | Citations |
|---|---|---|---|
| 38216672 | 2024 | TKT-PARP1 axis induces radioresistance by promoting DNA double-strand break repair in hepatocellular carcinoma. | 0 |
| 38216672 | 2024 | TKT-PARP1 axis induces radioresistance by promoting DNA double-strand break repair in hepatocellular carcinoma. | 0 |
| 35110545 | 2022 | Transketolase promotes colorectal cancer metastasis through regulating AKT phosphorylation. | 19 |
| 35110545 | 2022 | Transketolase promotes colorectal cancer metastasis through regulating AKT phosphorylation. | 19 |
| 34161071 | 2021 | QM/MM Study of Human Transketolase: Thiamine Diphosphate Activation Mechanism and Complete Catalytic Cycle. | 1 |
| 34161071 | 2021 | QM/MM Study of Human Transketolase: Thiamine Diphosphate Activation Mechanism and Complete Catalytic Cycle. | 1 |
| 31949131 | 2020 | The nuclear translocation of transketolase inhibits the farnesoid receptor expression by promoting the binding of HDAC3 to FXR promoter in hepatocellular carcinoma cell lines. | 16 |
| 32659474 | 2020 | Genetic variants in TKT and DERA in the nicotinamide adenine dinucleotide phosphate pathway predict melanoma survival. | 2 |
| 32828637 | 2020 | Untargeted metabolomics as an unbiased approach to the diagnosis of inborn errors of metabolism of the non-oxidative branch of the pentose phosphate pathway. | 6 |
| 31949131 | 2020 | The nuclear translocation of transketolase inhibits the farnesoid receptor expression by promoting the binding of HDAC3 to FXR promoter in hepatocellular carcinoma cell lines. | 16 |
| 32659474 | 2020 | Genetic variants in TKT and DERA in the nicotinamide adenine dinucleotide phosphate pathway predict melanoma survival. | 2 |
| 32828637 | 2020 | Untargeted metabolomics as an unbiased approach to the diagnosis of inborn errors of metabolism of the non-oxidative branch of the pentose phosphate pathway. | 6 |
| 30659097 | 2019 | Hepatitis B virus X protein-induced SH2 domain-containing 5 (SH2D5) expression promotes hepatoma cell growth via an SH2D5-transketolase interaction. | 15 |
| 31415630 | 2019 | Transketolase and vitamin B1 influence on ROS-dependent neutrophil extracellular traps (NETs) formation. | 7 |
| 31424204 | 2019 | Transketolase Activity in the Formation of the Azinomycin Azabicycle Moiety. | 2 |
Citation
Dessen P
TKT (transketolase)
Atlas Genet Cytogenet Oncol Haematol. 2013-05-01
Online version: http://atlasgeneticsoncology.org/gene/53265/tkt-(transketolase)
