Identity
HGNC
LOCATION
3q27.2
LOCUSID
ALIAS
AXAM2,SMT3IP2
FUSION GENES
Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, contribute in submission tool
Other Information
Locus ID:
NCBI: 59343
MIM: 608261
HGNC: 23116
Ensembl: ENSG00000163904
Variants:
dbSNP: 59343
ClinVar: 59343
TCGA: ENSG00000163904
COSMIC: SENP2
RNA/Proteins
Expression (GTEx)
Pathways
Protein levels (Protein atlas)
References
| Pubmed ID | Year | Title | Citations |
|---|---|---|---|
| 36708515 | 2023 | Mitochondrial SENP2 regulates the assembly of SDH complex under metabolic stress. | 5 |
| 36708515 | 2023 | Mitochondrial SENP2 regulates the assembly of SDH complex under metabolic stress. | 5 |
| 35064188 | 2022 | SENP2 regulates mitochondrial function and insulin secretion in pancreatic β cells. | 6 |
| 35064188 | 2022 | SENP2 regulates mitochondrial function and insulin secretion in pancreatic β cells. | 6 |
| 33934381 | 2021 | Hepatic Small Ubiquitin-Related Modifier (SUMO)-Specific Protease 2 Controls Systemic Metabolism Through SUMOylation-Dependent Regulation of Liver-Adipose Tissue Crosstalk. | 15 |
| 33934381 | 2021 | Hepatic Small Ubiquitin-Related Modifier (SUMO)-Specific Protease 2 Controls Systemic Metabolism Through SUMOylation-Dependent Regulation of Liver-Adipose Tissue Crosstalk. | 15 |
| 31964975 | 2020 | Silencing of SENP2 in Multiple Myeloma Induces Bortezomib Resistance by Activating NF-κB Through the Modulation of IκBα Sumoylation. | 15 |
| 31964975 | 2020 | Silencing of SENP2 in Multiple Myeloma Induces Bortezomib Resistance by Activating NF-κB Through the Modulation of IκBα Sumoylation. | 15 |
| 30431078 | 2019 | SENP2 exerts an anti‑tumor effect on chronic lymphocytic leukemia cells through the inhibition of the Notch and NF‑κB signaling pathways. | 6 |
| 30796017 | 2019 | The deSUMOylase SENP2 coordinates homologous recombination and nonhomologous end joining by independent mechanisms. | 23 |
| 30997579 | 2019 | Comprehensive Analysis of the Canonical and Non-canonical Wnt Signaling Pathways in Gastric Cancer. | 6 |
| 30431078 | 2019 | SENP2 exerts an anti‑tumor effect on chronic lymphocytic leukemia cells through the inhibition of the Notch and NF‑κB signaling pathways. | 6 |
| 30796017 | 2019 | The deSUMOylase SENP2 coordinates homologous recombination and nonhomologous end joining by independent mechanisms. | 23 |
| 30997579 | 2019 | Comprehensive Analysis of the Canonical and Non-canonical Wnt Signaling Pathways in Gastric Cancer. | 6 |
| 29146736 | 2018 | Quantitative high-throughput screening identifies cytoprotective molecules that enhance SUMO conjugation via the inhibition of SUMO-specific protease (SENP)2. | 24 |
Citation
Dessen P
SENP2 (SUMO specific peptidase 2)
Atlas Genet Cytogenet Oncol Haematol. 2013-05-01
Online version: http://atlasgeneticsoncology.org/gene/53271/senp2-(sumo-specific-peptidase-2)
