GOLGA2 (golgin A2)

2013-05-01  

Identity

HGNC
LOCATION
9q34.11
LOCUSID
ALIAS
GM130
FUSION GENES

Other Information

Locus ID:

NCBI: 2801
MIM: 602580
HGNC: 4425
Ensembl: ENSG00000167110

Variants:

dbSNP: 2801
ClinVar: 2801
TCGA: ENSG00000167110
COSMIC: GOLGA2

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000167110ENST00000421699Q08379
ENSG00000167110ENST00000421699A0A2Q2TH77
ENSG00000167110ENST00000450617B7ZC06
ENSG00000167110ENST00000458730H0Y7B8
ENSG00000167110ENST00000490628R4GND7
ENSG00000167110ENST00000610329A0A087WYC0
ENSG00000167110ENST00000611957Q08379
ENSG00000167110ENST00000639983A0A1W2PQY5

Expression (GTEx)

0
50
100
150

Pathways

PathwaySourceExternal ID
Metabolism of proteinsREACTOMER-HSA-392499
Post-translational protein modificationREACTOMER-HSA-597592
Asparagine N-linked glycosylationREACTOMER-HSA-446203
Transport to the Golgi and subsequent modificationREACTOMER-HSA-948021
ER to Golgi Anterograde TransportREACTOMER-HSA-199977
COPII (Coat Protein 2) Mediated Vesicle TransportREACTOMER-HSA-204005
DiseaseREACTOMER-HSA-1643685
Cell CycleREACTOMER-HSA-1640170
Cell Cycle, MitoticREACTOMER-HSA-69278
M PhaseREACTOMER-HSA-68886
Mitotic ProphaseREACTOMER-HSA-68875
Golgi Cisternae Pericentriolar Stack ReorganizationREACTOMER-HSA-162658
Vesicle-mediated transportREACTOMER-HSA-5653656
Membrane TraffickingREACTOMER-HSA-199991
COPI-mediated anterograde transportREACTOMER-HSA-6807878
Neurodegenerative DiseasesREACTOMER-HSA-8863678
Deregulated CDK5 triggers multiple neurodegenerative pathways in Alzheimer's disease modelsREACTOMER-HSA-8862803

Protein levels (Protein atlas)

Not detected
Low
Medium
High

References

Pubmed IDYearTitleCitations
376354092023WDR38, a novel equatorial segment protein, interacts with the GTPase protein RAB19 and Golgi protein GM130 to play roles in acrosome biogenesis.0
376354092023WDR38, a novel equatorial segment protein, interacts with the GTPase protein RAB19 and Golgi protein GM130 to play roles in acrosome biogenesis.0
358694902022Associations of IFT20 and GM130 protein expressions with clinicopathological features and survival of patients with lung adenocarcinoma.2
358694902022Associations of IFT20 and GM130 protein expressions with clinicopathological features and survival of patients with lung adenocarcinoma.2
344245532021Bi-allelic loss of function variants in GOLGA2 are associated with a complex neurological phenotype: Report of a second family.6
344245532021Bi-allelic loss of function variants in GOLGA2 are associated with a complex neurological phenotype: Report of a second family.6
309272042020Identification and Verification of Two Novel Differentially Expressed Proteins from Non-neoplastic Mucosa and Colorectal Carcinoma Via iTRAQ Combined with Liquid Chromatography-Mass Spectrometry.3
318330552020Liquid-liquid phase separation of the Golgi matrix protein GM130.28
323318362020Markers of malignant prostate cancer cells: Golgi localization of α-mannosidase 1A at GM130-GRASP65 site and appearance of high mannose N-glycans on cell surface.11
309272042020Identification and Verification of Two Novel Differentially Expressed Proteins from Non-neoplastic Mucosa and Colorectal Carcinoma Via iTRAQ Combined with Liquid Chromatography-Mass Spectrometry.3
318330552020Liquid-liquid phase separation of the Golgi matrix protein GM130.28
323318362020Markers of malignant prostate cancer cells: Golgi localization of α-mannosidase 1A at GM130-GRASP65 site and appearance of high mannose N-glycans on cell surface.11
307099702019A SEPT1-based scaffold is required for Golgi integrity and function.12
308162002019DGAT1 Inhibitor Suppresses Prostate Tumor Growth and Migration by Regulating Intracellular Lipids and Non-Centrosomal MTOC Protein GM130.24
309173632019Loss of the Golgi Matrix Protein 130 Cause Aberrant IgA1 Glycosylation in IgA Nephropathy.8

Citation

Dessen P

GOLGA2 (golgin A2)

Atlas Genet Cytogenet Oncol Haematol. 2013-05-01

Online version: http://atlasgeneticsoncology.org/gene/53275/golga2-(golgin-a2)