FBXO10 (F-box protein 10)

2013-05-01  

Identity

HGNC
LOCATION
9p13.2
LOCUSID
ALIAS
FBX10,PRMT11
FUSION GENES

Other Information

Locus ID:

NCBI: 26267
MIM: 609092
HGNC: 13589
Ensembl: ENSG00000256966

Variants:

dbSNP: 26267
ClinVar: 26267
TCGA: ENSG00000256966
COSMIC: FBXO10

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000256966ENST00000537239H3BUX3

Pathways

PathwaySourceExternal ID
Immune SystemREACTOMER-HSA-168256
Adaptive Immune SystemREACTOMER-HSA-1280218
Class I MHC mediated antigen processing & presentationREACTOMER-HSA-983169
Antigen processing: Ubiquitination & Proteasome degradationREACTOMER-HSA-983168

References

Pubmed IDYearTitleCitations
315707562020Recent BCR stimulation induces a negative autoregulatory loop via FBXO10 mediated degradation of HGAL.8
315707562020Recent BCR stimulation induces a negative autoregulatory loop via FBXO10 mediated degradation of HGAL.8
261876702015FBXO11 represses cellular response to hypoxia by destabilizing hypoxia-inducible factor-1α mRNA.12
261876702015FBXO11 represses cellular response to hypoxia by destabilizing hypoxia-inducible factor-1α mRNA.12
231389332014Human MCS5A1 candidate breast cancer susceptibility gene FBXO10 is induced by cellular stress and correlated with lens epithelium-derived growth factor (LEDGF).15
231389332014Human MCS5A1 candidate breast cancer susceptibility gene FBXO10 is induced by cellular stress and correlated with lens epithelium-derived growth factor (LEDGF).15
234311382013Related F-box proteins control cell death in Caenorhabditis elegans and human lymphoma.37
234311382013Related F-box proteins control cell death in Caenorhabditis elegans and human lymphoma.37
203796142010Personalized smoking cessation: interactions between nicotine dose, dependence and quit-success genotype score.78
205547492010FGFR2 and other loci identified in genome-wide association studies are associated with breast cancer in African-American and younger women.69
203796142010Personalized smoking cessation: interactions between nicotine dose, dependence and quit-success genotype score.78
205547492010FGFR2 and other loci identified in genome-wide association studies are associated with breast cancer in African-American and younger women.69
191245062009Common genetic variation in candidate genes and susceptibility to subtypes of breast cancer.27
191245062009Common genetic variation in candidate genes and susceptibility to subtypes of breast cancer.27

Citation

Dessen P

FBXO10 (F-box protein 10)

Atlas Genet Cytogenet Oncol Haematol. 2013-05-01

Online version: http://atlasgeneticsoncology.org/gene/53297/fbxo10-(f-box-protein-10)