FCGR1A (Fc fragment of IgG receptor Ia)

2013-05-01  

Identity

HGNC
LOCATION
1q21.2
LOCUSID
ALIAS
CD64,CD64A,FCRI,IGFR1

Other Information

Locus ID:

NCBI: 2209
MIM: 146760
HGNC: 3613
Ensembl: ENSG00000150337

Variants:

dbSNP: 2209
ClinVar: 2209
TCGA: ENSG00000150337
COSMIC: FCGR1A

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000150337ENST00000369168P12314
ENSG00000150337ENST00000444948C9JSN8

Expression (GTEx)

0
5
10
15
20
25
30
35

Pathways

PathwaySourceExternal ID
Hematopoietic cell lineageKEGGko04640
Systemic lupus erythematosusKEGGko05322
Hematopoietic cell lineageKEGGhsa04640
Systemic lupus erythematosusKEGGhsa05322
Fc gamma R-mediated phagocytosisKEGGko04666
Fc gamma R-mediated phagocytosisKEGGhsa04666
LeishmaniasisKEGGko05140
LeishmaniasisKEGGhsa05140
PhagosomeKEGGko04145
PhagosomeKEGGhsa04145
Staphylococcus aureus infectionKEGGko05150
Staphylococcus aureus infectionKEGGhsa05150
Osteoclast differentiationKEGGko04380
Osteoclast differentiationKEGGhsa04380
TuberculosisKEGGko05152
TuberculosisKEGGhsa05152
Transcriptional misregulation in cancerKEGGko05202
Transcriptional misregulation in cancerKEGGhsa05202
Immune SystemREACTOMER-HSA-168256
Adaptive Immune SystemREACTOMER-HSA-1280218
Class I MHC mediated antigen processing & presentationREACTOMER-HSA-983169
Antigen processing-Cross presentationREACTOMER-HSA-1236975
Cross-presentation of soluble exogenous antigens (endosomes)REACTOMER-HSA-1236978
Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cellREACTOMER-HSA-198933
Innate Immune SystemREACTOMER-HSA-168249
Fcgamma receptor (FCGR) dependent phagocytosisREACTOMER-HSA-2029480
FCGR activationREACTOMER-HSA-2029481
Regulation of actin dynamics for phagocytic cup formationREACTOMER-HSA-2029482
Role of phospholipids in phagocytosisREACTOMER-HSA-2029485
Cytokine Signaling in Immune systemREACTOMER-HSA-1280215
Interferon SignalingREACTOMER-HSA-913531
Interferon gamma signalingREACTOMER-HSA-877300

References

Pubmed IDYearTitleCitations
384246432024Neutrophil CD64 index as a new early predictive biomarker for infected pancreatic necrosis in acute pancreatitis.0
384246432024Neutrophil CD64 index as a new early predictive biomarker for infected pancreatic necrosis in acute pancreatitis.0
373106912023CD64 expression on neutrophils as a potential biomarker for bacterial infection in ascitic fluid of cirrhotic patients.0
373523782023Prognostic performance of neutrophil CD64 expression in patients with complicated intra-abdominal infections - a prospective study.1
379586952023A Non-Coding Fc Gamma Receptor Cis-Regulatory Variant within the 1q23 Gene Cluster Is Associated with Plasmodium falciparum Infection in Children Residing in Burkina Faso.0
373106912023CD64 expression on neutrophils as a potential biomarker for bacterial infection in ascitic fluid of cirrhotic patients.0
373523782023Prognostic performance of neutrophil CD64 expression in patients with complicated intra-abdominal infections - a prospective study.1
379586952023A Non-Coding Fc Gamma Receptor Cis-Regulatory Variant within the 1q23 Gene Cluster Is Associated with Plasmodium falciparum Infection in Children Residing in Burkina Faso.0
353710202022Novel Human FCGR1A Variants Affect CD64 Functions and Are Risk Factors for Sarcoidosis.2
359077852022Multi-marker approach using C-reactive protein, procalcitonin, neutrophil CD64 index for the prognosis of sepsis in intensive care unit: a retrospective cohort study.3
353710202022Novel Human FCGR1A Variants Affect CD64 Functions and Are Risk Factors for Sarcoidosis.2
359077852022Multi-marker approach using C-reactive protein, procalcitonin, neutrophil CD64 index for the prognosis of sepsis in intensive care unit: a retrospective cohort study.3
331606252021CD64, CD11a and CD18 leukocytes expression in children with SARS-CoV-2 multisystem inflammatory syndrome versus children with Kawasaki disease: Similar but not the same.2
334919212021CD169 and CD64 could help differentiate bacterial from CoVID-19 or other viral infections in the Emergency Department.21
343234242021Fcγ receptor activation mediates vascular inflammation and abdominal aortic aneurysm development.9

Citation

Dessen P

FCGR1A (Fc fragment of IgG receptor Ia)

Atlas Genet Cytogenet Oncol Haematol. 2013-05-01

Online version: http://atlasgeneticsoncology.org/gene/53298/