Identity
HGNC
LOCATION
2p16.2
LOCUSID
ALIAS
ELF,HEL102,SPTB2,betaSpII
FUSION GENES
Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, contribute in submission tool
Other Information
Locus ID:
NCBI: 6711
MIM: 182790
HGNC: 11275
Ensembl: ENSG00000115306
Variants:
dbSNP: 6711
ClinVar: 6711
TCGA: ENSG00000115306
COSMIC: SPTBN1
RNA/Proteins
Expression (GTEx)
Pathways
Protein levels (Protein atlas)
References
| Pubmed ID | Year | Title | Citations |
|---|---|---|---|
| 37921259 | 2024 | Tumor cell SPTBN1 inhibits M2 polarization of macrophages by suppressing CXCL1 expression. | 1 |
| 38683846 | 2024 | Identification of bone mineral density associated genes with shared genetic architectures across multiple tissues: Functional insights for EPDR1, PKDCC, and SPTBN1. | 0 |
| 37921259 | 2024 | Tumor cell SPTBN1 inhibits M2 polarization of macrophages by suppressing CXCL1 expression. | 1 |
| 38683846 | 2024 | Identification of bone mineral density associated genes with shared genetic architectures across multiple tissues: Functional insights for EPDR1, PKDCC, and SPTBN1. | 0 |
| 37013511 | 2023 | Clinical significance of nonerythrocytic spectrin Beta 1 (SPTBN1) in human kidney renal clear cell carcinoma and uveal melanoma: a study based on Pan-Cancer Analysis. | 3 |
| 38069214 | 2023 | SPTBN1 Mediates the Cytoplasmic Constraint of PTTG1, Impairing Its Oncogenic Activity in Human Seminoma. | 0 |
| 37013511 | 2023 | Clinical significance of nonerythrocytic spectrin Beta 1 (SPTBN1) in human kidney renal clear cell carcinoma and uveal melanoma: a study based on Pan-Cancer Analysis. | 3 |
| 38069214 | 2023 | SPTBN1 Mediates the Cytoplasmic Constraint of PTTG1, Impairing Its Oncogenic Activity in Human Seminoma. | 0 |
| 36444616 | 2022 | SPTBN1 attenuates rheumatoid arthritis synovial cell proliferation, invasion, migration and inflammatory response by binding to PIK3R2. | 1 |
| 36527113 | 2022 | SPTBN1 abrogates renal clear cell carcinoma progression via glycolysis reprogramming in a GPT2-dependent manner. | 4 |
| 36444616 | 2022 | SPTBN1 attenuates rheumatoid arthritis synovial cell proliferation, invasion, migration and inflammatory response by binding to PIK3R2. | 1 |
| 36527113 | 2022 | SPTBN1 abrogates renal clear cell carcinoma progression via glycolysis reprogramming in a GPT2-dependent manner. | 4 |
| 33390831 | 2021 | βII spectrin (SPTBN1): biological function and clinical potential in cancer and other diseases. | 30 |
| 33754058 | 2021 | SPTBN1 inhibits inflammatory responses and hepatocarcinogenesis via the stabilization of SOCS1 and downregulation of p65 in hepatocellular carcinoma. | 14 |
| 33847457 | 2021 | Heterozygous variants in SPTBN1 cause intellectual disability and autism. | 6 |
Citation
Dessen P
SPTBN1 (spectrin beta, non-erythrocytic 1)
Atlas Genet Cytogenet Oncol Haematol. 2007-10-01
Online version: http://atlasgeneticsoncology.org/gene/53313/sptbn1-(spectrin-beta-non-erythrocytic-1)
