VAMP7 (vesicle associated membrane protein 7)

2013-05-01  

Identity

HGNC
LOCATION
Xq28
LOCUSID
ALIAS
SYBL1,TI-VAMP,TIVAMP,VAMP-7

Other Information

Locus ID:

NCBI: 6845
MIM: 300053
HGNC: 11486
Ensembl: ENSG00000124333

Variants:

dbSNP: 6845
ClinVar: 6845
TCGA: ENSG00000124333
COSMIC: VAMP7

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000124333ENST00000262640P51809
ENSG00000124333ENST00000262640A0A024R074
ENSG00000124333ENST00000286448P51809
ENSG00000124333ENST00000286448A0A024R061
ENSG00000124333ENST00000460621P51809
ENSG00000124333ENST00000488344E5RH06

Expression (GTEx)

0
10
20
30
40
50
60

Pathways

PathwaySourceExternal ID
SNARE interactions in vesicular transportKEGGko04130
SNARE interactions in vesicular transportKEGGhsa04130
Vesicle-mediated transportREACTOMER-HSA-5653656
Membrane TraffickingREACTOMER-HSA-199991
trans-Golgi Network Vesicle BuddingREACTOMER-HSA-199992
Clathrin derived vesicle buddingREACTOMER-HSA-421837
Golgi Associated Vesicle BiogenesisREACTOMER-HSA-432722
Lysosome Vesicle BiogenesisREACTOMER-HSA-432720
Clathrin-mediated endocytosisREACTOMER-HSA-8856828
Cargo recognition for clathrin-mediated endocytosisREACTOMER-HSA-8856825

Protein levels (Protein atlas)

Not detected
Low
Medium
High

References

Pubmed IDYearTitleCitations
381828882024The STX17-SNAP47-VAMP7/VAMP8 complex is the default SNARE complex mediating autophagosome-lysosome fusion.3
383939342024Upregulation of vesicle-associated membrane protein 7 in breast cancer tissues.0
381828882024The STX17-SNAP47-VAMP7/VAMP8 complex is the default SNARE complex mediating autophagosome-lysosome fusion.3
383939342024Upregulation of vesicle-associated membrane protein 7 in breast cancer tissues.0
381391552023VAMP7j: A Splice Variant of Human VAMP7 That Modulates Neurite Outgrowth by Regulating L1CAM Transport to the Plasma Membrane.0
381391552023VAMP7j: A Splice Variant of Human VAMP7 That Modulates Neurite Outgrowth by Regulating L1CAM Transport to the Plasma Membrane.0
350822832022The EMT-induced lncRNA NR2F1-AS1 positively modulates NR2F1 expression and drives gastric cancer via miR-29a-3p/VAMP7 axis.30
350822832022The EMT-induced lncRNA NR2F1-AS1 positively modulates NR2F1 expression and drives gastric cancer via miR-29a-3p/VAMP7 axis.30
338869572021A BLOC-1-AP-3 super-complex sorts a cis-SNARE complex into endosome-derived tubular transport carriers.6
340421622021Organelle tethering, pore formation and SNARE compensation in the late endocytic pathway.4
340883372021LINC00511 drives invasive behavior in hepatocellular carcinoma by regulating exosome secretion and invadopodia formation.22
338869572021A BLOC-1-AP-3 super-complex sorts a cis-SNARE complex into endosome-derived tubular transport carriers.6
340421622021Organelle tethering, pore formation and SNARE compensation in the late endocytic pathway.4
340883372021LINC00511 drives invasive behavior in hepatocellular carcinoma by regulating exosome secretion and invadopodia formation.22
312511112020DIPK2A promotes STX17- and VAMP7-mediated autophagosome-lysosome fusion by binding to VAMP7B.21

Citation

Dessen P

VAMP7 (vesicle associated membrane protein 7)

Atlas Genet Cytogenet Oncol Haematol. 2013-05-01

Online version: http://atlasgeneticsoncology.org/gene/53320/vamp7-(vesicle-associated-membrane-protein-7)