SVIL (supervillin)

2013-06-01  

Identity

HGNC
LOCATION
10p11.23
LOCUSID
ALIAS
MFM10
FUSION GENES

Other Information

Locus ID:

NCBI: 6840
MIM: 604126
HGNC: 11480
Ensembl: ENSG00000197321

Variants:

dbSNP: 6840
ClinVar: 6840
TCGA: ENSG00000197321
COSMIC: SVIL

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000197321ENST00000355867O95425
ENSG00000197321ENST00000375398O95425
ENSG00000197321ENST00000375400O95425
ENSG00000197321ENST00000632315A0A0J9YWY6

Expression (GTEx)

0
50
100
150
200
250
300
350
400
450

Protein levels (Protein atlas)

Not detected
Low
Medium
High

References

Pubmed IDYearTitleCitations
344802492022Supervillin Contributes to LPS-induced Inflammatory Response in THP-1 Cell-derived Macrophages.2
344802492022Supervillin Contributes to LPS-induced Inflammatory Response in THP-1 Cell-derived Macrophages.2
338621012021Molecular basis of functional exchangeability between ezrin and other actin-membrane associated proteins during cytokinesis.1
338621012021Molecular basis of functional exchangeability between ezrin and other actin-membrane associated proteins during cytokinesis.1
324680642020Supervillin promotes tumor angiogenesis in liver cancer.4
325829732020A twin‑pair analysis indicates congenital scoliosis is associated with allele‑specific methylation in the SVIL gene.1
327797032020Loss of supervillin causes myopathy with myofibrillar disorganization and autophagic vacuoles.12
324680642020Supervillin promotes tumor angiogenesis in liver cancer.4
325829732020A twin‑pair analysis indicates congenital scoliosis is associated with allele‑specific methylation in the SVIL gene.1
327797032020Loss of supervillin causes myopathy with myofibrillar disorganization and autophagic vacuoles.12
256056652015Gamma-sarcoglycan is required for the response of archvillin to mechanical stimulation in skeletal muscle.14
256842062015A specific LSD1/KDM1A isoform regulates neuronal differentiation through H3K9 demethylation.130
256056652015Gamma-sarcoglycan is required for the response of archvillin to mechanical stimulation in skeletal muscle.14
256842062015A specific LSD1/KDM1A isoform regulates neuronal differentiation through H3K9 demethylation.130
233823812013Supervillin-mediated suppression of p53 protein enhances cell survival.21

Citation

Dessen P

SVIL (supervillin)

Atlas Genet Cytogenet Oncol Haematol. 2013-06-01

Online version: http://atlasgeneticsoncology.org/gene/53334/svil-(supervillin)