Identity
HGNC
LOCATION
10q23.2
LOCUSID
ALIAS
ATPSK2,BCYM4,SK2
FUSION GENES
Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, contribute in submission tool
Other Information
Locus ID:
NCBI: 9060
MIM: 603005
HGNC: 8604
Ensembl: ENSG00000198682
Variants:
dbSNP: 9060
ClinVar: 9060
TCGA: ENSG00000198682
COSMIC: PAPSS2
RNA/Proteins
| Gene ID | Transcript ID | Uniprot |
|---|---|---|
| ENSG00000198682 | ENST00000361175 | O95340 |
| ENSG00000198682 | ENST00000361175 | Q5TB52 |
| ENSG00000198682 | ENST00000456849 | O95340 |
Expression (GTEx)
Pathways
Protein levels (Protein atlas)
References
| Pubmed ID | Year | Title | Citations |
|---|---|---|---|
| 38084048 | 2024 | Bone Phenotype is Always Present But Androgen Excess is Less Frequently Seen in PAPSS2 Deficiency. | 0 |
| 38084048 | 2024 | Bone Phenotype is Always Present But Androgen Excess is Less Frequently Seen in PAPSS2 Deficiency. | 0 |
| 37207644 | 2023 | Redox switching mechanism of the adenosine 5'-phosphosulfate kinase domain (APSK2) of human PAPS synthase 2. | 0 |
| 37207644 | 2023 | Redox switching mechanism of the adenosine 5'-phosphosulfate kinase domain (APSK2) of human PAPS synthase 2. | 0 |
| 34818583 | 2022 | Structural basis for the substrate recognition mechanism of ATP-sulfurylase domain of human PAPS synthase 2. | 4 |
| 35261200 | 2022 | Identification of variants in ACAN and PAPSS2 leading to spondyloepi(meta)physeal dysplasias in four Chinese families. | 3 |
| 34818583 | 2022 | Structural basis for the substrate recognition mechanism of ATP-sulfurylase domain of human PAPS synthase 2. | 4 |
| 35261200 | 2022 | Identification of variants in ACAN and PAPSS2 leading to spondyloepi(meta)physeal dysplasias in four Chinese families. | 3 |
| 33819483 | 2021 | Intestinal Sulfation Is Essential to Protect Against Colitis and Colonic Carcinogenesis. | 22 |
| 33819483 | 2021 | Intestinal Sulfation Is Essential to Protect Against Colitis and Colonic Carcinogenesis. | 22 |
| 29955124 | 2019 | Enhanced PAPSS2/VCAN sulfation axis is essential for Snail-mediated breast cancer cell migration and metastasis. | 52 |
| 31313512 | 2019 | PAPSS2-related brachyolmia: Clinical and radiological phenotype in 18 new cases. | 10 |
| 29955124 | 2019 | Enhanced PAPSS2/VCAN sulfation axis is essential for Snail-mediated breast cancer cell migration and metastasis. | 52 |
| 31313512 | 2019 | PAPSS2-related brachyolmia: Clinical and radiological phenotype in 18 new cases. | 10 |
| 29743239 | 2018 | Human DHEA sulfation requires direct interaction between PAPS synthase 2 and DHEA sulfotransferase SULT2A1. | 15 |
Citation
Dessen P
PAPSS2 (3-phosphoadenosine 5-phosphosulfate synthase 2)
Atlas Genet Cytogenet Oncol Haematol. 2013-06-01
Online version: http://atlasgeneticsoncology.org/gene/53351/papss2-(3-phosphoadenosine-5-phosphosulfate-synthase-2)
