Identity
HGNC
LOCATION
8q11.23
LOCUSID
ALIAS
APT-1,APT1,LPL-I,LPL1,hAPT1
FUSION GENES
Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, contribute in submission tool
Other Information
Locus ID:
NCBI: 10434
MIM: 605599
HGNC: 6737
Ensembl: ENSG00000120992
Variants:
dbSNP: 10434
ClinVar: 10434
TCGA: ENSG00000120992
COSMIC: LYPLA1
RNA/Proteins
Expression (GTEx)
Pathways
Protein levels (Protein atlas)
References
| Pubmed ID | Year | Title | Citations |
|---|---|---|---|
| 38179877 | 2024 | A conserved but structurally divergent loop in acyl protein thioesterase 1 regulates its catalytic activity, ligand binding, and folded stability. | 0 |
| 38344800 | 2024 | Depalmitoylation and cell physiology: APT1 as a mediator of metabolic signals. | 0 |
| 38179877 | 2024 | A conserved but structurally divergent loop in acyl protein thioesterase 1 regulates its catalytic activity, ligand binding, and folded stability. | 0 |
| 38344800 | 2024 | Depalmitoylation and cell physiology: APT1 as a mediator of metabolic signals. | 0 |
| 34984578 | 2022 | LncRNA LOXL1-AS1 Facilitates the Oncogenic Character in Cervical Cancer by the miR-526b-5p /LYPLA1 Axis. | 5 |
| 34984578 | 2022 | LncRNA LOXL1-AS1 Facilitates the Oncogenic Character in Cervical Cancer by the miR-526b-5p /LYPLA1 Axis. | 5 |
| 30431103 | 2019 | Inhibition of cell proliferation and migration in non‑small cell lung cancer cells through the suppression of LYPLA1. | 13 |
| 30482805 | 2019 | Lysophospholipases cooperate to mediate lipid homeostasis and lysophospholipid signaling. | 22 |
| 30431103 | 2019 | Inhibition of cell proliferation and migration in non‑small cell lung cancer cells through the suppression of LYPLA1. | 13 |
| 30482805 | 2019 | Lysophospholipases cooperate to mediate lipid homeostasis and lysophospholipid signaling. | 22 |
| 29295957 | 2018 | The depalmitoylase APT1 directs the asymmetric partitioning of Notch and Wnt signaling during cell division. | 10 |
| 29362370 | 2018 | Active and dynamic mitochondrial S-depalmitoylation revealed by targeted fluorescent probes. | 40 |
| 29295957 | 2018 | The depalmitoylase APT1 directs the asymmetric partitioning of Notch and Wnt signaling during cell division. | 10 |
| 29362370 | 2018 | Active and dynamic mitochondrial S-depalmitoylation revealed by targeted fluorescent probes. | 40 |
| 25670628 | 2015 | miRs-138 and -424 control palmitoylation-dependent CD95-mediated cell death by targeting acyl protein thioesterases 1 and 2 in CLL. | 23 |
Citation
Dessen P
LYPLA1 (lysophospholipase 1)
Atlas Genet Cytogenet Oncol Haematol. 2013-06-01
Online version: http://atlasgeneticsoncology.org/gene/53380/
