Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, contribute in submission tool
Other Information
Locus ID:
NCBI: 8502
MIM: 604276
HGNC: 9026
Ensembl: ENSG00000144283
Variants:
dbSNP: 8502
ClinVar: 8502
TCGA: ENSG00000144283
COSMIC: PKP4
RNA/Proteins
Expression (GTEx)
Pathways
| Pathway | Source | External ID |
|---|---|---|
| Developmental Biology | REACTOME | R-HSA-1266738 |
| Keratinization | REACTOME | R-HSA-6805567 |
| Formation of the cornified envelope | REACTOME | R-HSA-6809371 |
Protein levels (Protein atlas)
References
| Pubmed ID | Year | Title | Citations |
|---|---|---|---|
| 32541000 | 2020 | Kir2.1 Interactome Mapping Uncovers PKP4 as a Modulator of the Kir2.1-Regulated Inward Rectifier Potassium Currents. | 11 |
| 32541000 | 2020 | Kir2.1 Interactome Mapping Uncovers PKP4 as a Modulator of the Kir2.1-Regulated Inward Rectifier Potassium Currents. | 11 |
| 28898462 | 2018 | p0071 interacts with E-cadherin in the cytoplasm so as to promote the invasion and metastasis of non-small cell lung cancer. | 2 |
| 28898462 | 2018 | p0071 interacts with E-cadherin in the cytoplasm so as to promote the invasion and metastasis of non-small cell lung cancer. | 2 |
| 28808088 | 2017 | The armadillo protein p0071 controls KIF3 motor transport. | 4 |
| 28808088 | 2017 | The armadillo protein p0071 controls KIF3 motor transport. | 4 |
| 24163434 | 2014 | The armadillo protein p0071 is involved in Rab11-dependent recycling. | 5 |
| 24163434 | 2014 | The armadillo protein p0071 is involved in Rab11-dependent recycling. | 5 |
| 23640939 | 2013 | p0071/PKP4, a multifunctional protein coordinating cell adhesion with cytoskeletal organization. | 20 |
| 23640939 | 2013 | p0071/PKP4, a multifunctional protein coordinating cell adhesion with cytoskeletal organization. | 20 |
| 22965878 | 2012 | Folliculin interacts with p0071 (plakophilin-4) and deficiency is associated with disordered RhoA signalling, epithelial polarization and cytokinesis. | 23 |
| 23139756 | 2012 | Folliculin, the product of the Birt-Hogg-Dube tumor suppressor gene, interacts with the adherens junction protein p0071 to regulate cell-cell adhesion. | 35 |
| 22965878 | 2012 | Folliculin interacts with p0071 (plakophilin-4) and deficiency is associated with disordered RhoA signalling, epithelial polarization and cytokinesis. | 23 |
| 23139756 | 2012 | Folliculin, the product of the Birt-Hogg-Dube tumor suppressor gene, interacts with the adherens junction protein p0071 to regulate cell-cell adhesion. | 35 |
| 19830446 | 2010 | Protein p0071, an armadillo plaque protein of adherens junctions, is predominantly expressed in distal renal tubules. | 2 |
Citation
Dessen P
PKP4 (plakophilin 4)
Atlas Genet Cytogenet Oncol Haematol. 2013-06-01
Online version: http://atlasgeneticsoncology.org/gene/53383/pkp4
