Identity
HGNC
LOCATION
3q13.31
LOCUSID
ALIAS
B-50,GAP-43,PP46
FUSION GENES
Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, contribute in submission tool
Other Information
Locus ID:
NCBI: 2596
MIM: 162060
HGNC: 4140
Ensembl: ENSG00000172020
Variants:
dbSNP: 2596
ClinVar: 2596
TCGA: ENSG00000172020
COSMIC: GAP43
RNA/Proteins
| Gene ID | Transcript ID | Uniprot |
|---|---|---|
| ENSG00000172020 | ENST00000305124 | P17677 |
| ENSG00000172020 | ENST00000305124 | Q5U058 |
| ENSG00000172020 | ENST00000393780 | P17677 |
Expression (GTEx)
Pathways
| Pathway | Source | External ID |
|---|---|---|
| Developmental Biology | REACTOME | R-HSA-1266738 |
| Axon guidance | REACTOME | R-HSA-422475 |
| L1CAM interactions | REACTOME | R-HSA-373760 |
Protein levels (Protein atlas)
References
| Pubmed ID | Year | Title | Citations |
|---|---|---|---|
| 38339928 | 2024 | Associations of Growth-Associated Protein 43 with Cerebral Microbleeds: A Longitudinal Study. | 0 |
| 38339928 | 2024 | Associations of Growth-Associated Protein 43 with Cerebral Microbleeds: A Longitudinal Study. | 0 |
| 36739296 | 2023 | Impact of GAP-43, Cx43 and actin expression on the outcome and overall survival in diffuse and anaplastic gliomas. | 1 |
| 36963347 | 2023 | Growth associated protein 43 deficiency promotes podocyte injury by activating the calmodulin/calcineurin pathway under hyperglycemia. | 0 |
| 37169842 | 2023 | GAP43-dependent mitochondria transfer from astrocytes enhances glioblastoma tumorigenicity. | 23 |
| 37852045 | 2023 | Association of APOE-ε4 and GAP-43-related presynaptic loss with β-amyloid, tau, neurodegeneration, and cognitive decline. | 1 |
| 36739296 | 2023 | Impact of GAP-43, Cx43 and actin expression on the outcome and overall survival in diffuse and anaplastic gliomas. | 1 |
| 36963347 | 2023 | Growth associated protein 43 deficiency promotes podocyte injury by activating the calmodulin/calcineurin pathway under hyperglycemia. | 0 |
| 37169842 | 2023 | GAP43-dependent mitochondria transfer from astrocytes enhances glioblastoma tumorigenicity. | 23 |
| 37852045 | 2023 | Association of APOE-ε4 and GAP-43-related presynaptic loss with β-amyloid, tau, neurodegeneration, and cognitive decline. | 1 |
| 35258850 | 2022 | Prognostic value of cutaneous reinnervation with GAP-43 in oxaliplatin-induced neuropathy. | 1 |
| 36383568 | 2022 | Cutaneous expression of growth-associated protein 43 is not a compelling marker for human nerve regeneration in carpal tunnel syndrome. | 0 |
| 36611808 | 2022 | Association of CSF GAP-43 and APOE ε4 with Cognition in Mild Cognitive Impairment and Alzheimer's Disease. | 3 |
| 35258850 | 2022 | Prognostic value of cutaneous reinnervation with GAP-43 in oxaliplatin-induced neuropathy. | 1 |
| 36383568 | 2022 | Cutaneous expression of growth-associated protein 43 is not a compelling marker for human nerve regeneration in carpal tunnel syndrome. | 0 |
Citation
Dessen P
GAP43 (growth associated protein 43)
Atlas Genet Cytogenet Oncol Haematol. 2013-06-01
Online version: http://atlasgeneticsoncology.org/gene/53398/gap43-(growth-associated-protein-43)
