Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, contribute in submission tool
Other Information
Locus ID:
NCBI: 3062
MIM: 602393
HGNC: 4849
Ensembl: ENSG00000137252
Variants:
dbSNP: 3062
ClinVar: 3062
TCGA: ENSG00000137252
COSMIC: HCRTR2
RNA/Proteins
| Gene ID | Transcript ID | Uniprot |
|---|---|---|
| ENSG00000137252 | ENST00000370862 | O43614 |
| ENSG00000137252 | ENST00000370862 | S4X0W3 |
| ENSG00000137252 | ENST00000615358 | O43614 |
| ENSG00000137252 | ENST00000615358 | S4X0W3 |
Expression (GTEx)
Pathways
Protein levels (Protein atlas)
References
| Pubmed ID | Year | Title | Citations |
|---|---|---|---|
| 36901420 | 2023 | Relationship between APOE, PER2, PER3 and OX2R Genetic Variants and Neuropsychiatric Symptoms in Patients with Alzheimer's Disease. | 1 |
| 37054895 | 2023 | Internal and external modulation factors of the orexin system (REVIEW). | 3 |
| 37418013 | 2023 | Combined genotype of HCRTR2 and CLOCK variants in a large family of cluster headache with familial periodicity phenotype. | 0 |
| 36901420 | 2023 | Relationship between APOE, PER2, PER3 and OX2R Genetic Variants and Neuropsychiatric Symptoms in Patients with Alzheimer's Disease. | 1 |
| 37054895 | 2023 | Internal and external modulation factors of the orexin system (REVIEW). | 3 |
| 37418013 | 2023 | Combined genotype of HCRTR2 and CLOCK variants in a large family of cluster headache with familial periodicity phenotype. | 0 |
| 33547286 | 2021 | Structures of active-state orexin receptor 2 rationalize peptide and small-molecule agonist recognition and receptor activation. | 42 |
| 34472713 | 2021 | Human adipose tissue is a putative direct target of daytime orexin with favorable metabolic effects: A cross-sectional study. | 1 |
| 33547286 | 2021 | Structures of active-state orexin receptor 2 rationalize peptide and small-molecule agonist recognition and receptor activation. | 42 |
| 34472713 | 2021 | Human adipose tissue is a putative direct target of daytime orexin with favorable metabolic effects: A cross-sectional study. | 1 |
| 31768945 | 2020 | Analysis of HCRTR2, GNB3, and ADH4 Gene Polymorphisms in a Southeastern European Caucasian Cluster Headache Population. | 5 |
| 31983458 | 2020 | Orexin A associates with inflammation by interacting with OX1R/OX2R receptor and activating prepro-Orexin in cancer tissues of gastric cancer patients. | 4 |
| 31768945 | 2020 | Analysis of HCRTR2, GNB3, and ADH4 Gene Polymorphisms in a Southeastern European Caucasian Cluster Headache Population. | 5 |
| 31983458 | 2020 | Orexin A associates with inflammation by interacting with OX1R/OX2R receptor and activating prepro-Orexin in cancer tissues of gastric cancer patients. | 4 |
| 30326460 | 2019 | The preliminary investigation of orexigenic hormone gene polymorphisms on posttraumatic stress disorder symptoms. | 6 |
Citation
Dessen P
HCRTR2 (hypocretin receptor 2)
Atlas Genet Cytogenet Oncol Haematol. 2013-07-01
Online version: http://atlasgeneticsoncology.org/gene/53420/hcrtr2-(hypocretin-receptor-2)
