NFIL3 (nuclear factor, interleukin 3 regulated)

2013-07-01  

Identity

HGNC
NFIL3
LOCATION
9q22.31
LOCUSID
4783
ALIAS
E4BP4,IL3BP1,NF-IL3A,NFIL3A
FUSION GENES
Show Gene Fusions

Other Information

Locus ID:

NCBI: 4783
MIM: 605327
HGNC: 7787
Ensembl: ENSG00000165030

Variants:

dbSNP: 4783
ClinVar: 4783
TCGA: ENSG00000165030
COSMIC: NFIL3

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000165030ENST00000297689Q16649
ENSG00000165030ENST00000297689A0A024R241

Expression (GTEx)

0
50
100
150
200
250
Adipose - Subcutaneous
Adipose - Visceral
Adrenal Gland
Artery - Aorta
Artery - Tibial
Bladder
Brain - Amygdala
Brain - Anterior cingulate cortex
Brain - Caudate
Brain - Cerebellar Hemisphere
Brain - Cerebellum
Brain - Cortex
Brain - Frontal Cortex
Brain - Hippocampus
Brain - Hypothalamus
Brain - Nucleus accumbens
Brain - Putamen
Brain - Spinal cord
Brain - Substantia nigra
Breast - Mammary Tissue
Cells - Cultured fibroblasts
Cells - EBV - transformed lymphocytes
Cervix - Ectocervix
Cervix - Endocervix
Colon - Sigmoid
Colon - Transverse
Esophagus - Gastroesophageal Junction
Esophagus - Mucosa
Esophagus - Muscularis
Fallopian Tube
Heart - Atrial Appendage
Heart - Left Ventricle
Kidney - Cortex
Kidney - Medulla
Liver
Lung
Minor Salivary Gland
Muscle - Skeletal
Nerve - Tibial
Ovary
Pancreas
Pituitary
Prostate
Skin - Not Sun Exposed
Skin - Sun Exposed
Small Intestine - Terminal Ileum
Spleen
Stomach
Testis
Thyroid
Uterus
Vagina
Whole Blood

Pathways

PathwaySourceExternal ID
Circadian ClockREACTOMER-HSA-400253
BMAL1:CLOCK,NPAS2 activates circadian gene expressionREACTOMER-HSA-1368108

Protein levels (Protein atlas)

Not detected
Low
Medium
High
cerebral cortex
cerebellum
hippocampus
caudate
thyroid gland
parathyroid gland
adrenal gland
nasopharynx
bronchus
lung
oral mucosa
salivary gland
esophagus
stomach 1
stomach 2
duodenum
small intestine
colon
rectum
liver
gallbladder
pancreas
kidney
urinary bladder
testis
epididymis
seminal vesicle
prostate
vagina
ovary
fallopian tube
endometrium 1
endometrium 2
cervix, uterine
placenta
breast
heart muscle
smooth muscle
skeletal muscle
soft tissue 1
soft tissue 2
adipose tissue
skin 1
skin 2
appendix
spleen
lymph node
tonsil
bone marrow

References

Pubmed IDYearTitleCitations
377416012024A Potential Role of NFIL3 in Atherosclerosis.0
381939732024The role of basic leucine zipper transcription factor E4BP4 in cancer: a review and update.0
383826702024Structural basis for specific DNA sequence recognition by the transcription factor NFIL3.0
377416012024A Potential Role of NFIL3 in Atherosclerosis.0
381939732024The role of basic leucine zipper transcription factor E4BP4 in cancer: a review and update.0
383826702024Structural basis for specific DNA sequence recognition by the transcription factor NFIL3.0
379338722023NFIL3 aggravates human coronary artery endothelial cell injury by promoting ITGAM transcription in Kawasaki disease.0
379338722023NFIL3 aggravates human coronary artery endothelial cell injury by promoting ITGAM transcription in Kawasaki disease.0
364391452022NFIL3 and its immunoregulatory role in rheumatoid arthritis patients.7
364391452022NFIL3 and its immunoregulatory role in rheumatoid arthritis patients.7
314778382020Cellular prion protein transcriptionally regulated by NFIL3 enhances lung cancer cell lamellipodium formation and migration through JNK signaling.18
321916362020E4BP4-mediated inhibition of T follicular helper cell differentiation is compromised in autoimmune diseases.18
330139242020Diurnal Rhythmicity Programs of Microbiota and Transcriptional Oscillation of Circadian Regulator, NFIL3.9
314778382020Cellular prion protein transcriptionally regulated by NFIL3 enhances lung cancer cell lamellipodium formation and migration through JNK signaling.18
321916362020E4BP4-mediated inhibition of T follicular helper cell differentiation is compromised in autoimmune diseases.18

Citation

Dessen P

NFIL3 (nuclear factor, interleukin 3 regulated)

Atlas Genet Cytogenet Oncol Haematol. 2013-07-01

Online version: http://atlasgeneticsoncology.org/gene/53422/nfil3-(nuclear-factor-interleukin-3-regulated)