Identity
HGNC
LOCATION
17q21.32
LOCUSID
ALIAS
HOX2,HOX2D,Hox-2.4
FUSION GENES
Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, contribute in submission tool
Other Information
Locus ID:
NCBI: 3218
MIM: 142963
HGNC: 5119
Ensembl: ENSG00000120068
Variants:
dbSNP: 3218
ClinVar: 3218
TCGA: ENSG00000120068
COSMIC: HOXB8
RNA/Proteins
| Gene ID | Transcript ID | Uniprot |
|---|---|---|
| ENSG00000120068 | ENST00000239144 | P17481 |
| ENSG00000120068 | ENST00000498634 | I3L383 |
| ENSG00000120068 | ENST00000576562 | I3L3R1 |
Expression (GTEx)
References
| Pubmed ID | Year | Title | Citations |
|---|---|---|---|
| 32989886 | 2021 | SNHG3/miR-2682-5p/HOXB8 promotes cell proliferation and migration in oral squamous cell carcinoma. | 10 |
| 34098015 | 2021 | LINC01116 boosts the progression of pituitary adenoma via regulating miR-744-5p/HOXB8 pathway. | 7 |
| 34432948 | 2021 | Pharmacological Inhibition of Core Regulatory Circuitry Liquid-liquid Phase Separation Suppresses Metastasis and Chemoresistance in Osteosarcoma. | 32 |
| 34445617 | 2021 | HOXB8 Counteracts MAPK/ERK Oncogenic Signaling in a Chicken Embryo Model of Neoplasia. | 2 |
| 32989886 | 2021 | SNHG3/miR-2682-5p/HOXB8 promotes cell proliferation and migration in oral squamous cell carcinoma. | 10 |
| 34098015 | 2021 | LINC01116 boosts the progression of pituitary adenoma via regulating miR-744-5p/HOXB8 pathway. | 7 |
| 34432948 | 2021 | Pharmacological Inhibition of Core Regulatory Circuitry Liquid-liquid Phase Separation Suppresses Metastasis and Chemoresistance in Osteosarcoma. | 32 |
| 34445617 | 2021 | HOXB8 Counteracts MAPK/ERK Oncogenic Signaling in a Chicken Embryo Model of Neoplasia. | 2 |
| 31591481 | 2020 | Oncogenic HOXB8 is driven by MYC-regulated super-enhancer and potentiates colorectal cancer invasiveness via BACH1. | 35 |
| 31646435 | 2020 | Homeobox B8 Targets Sterile Alpha Motif Domain-Containing Protein 9 and Drives Glioma Progression. | 10 |
| 31591481 | 2020 | Oncogenic HOXB8 is driven by MYC-regulated super-enhancer and potentiates colorectal cancer invasiveness via BACH1. | 35 |
| 31646435 | 2020 | Homeobox B8 Targets Sterile Alpha Motif Domain-Containing Protein 9 and Drives Glioma Progression. | 10 |
| 30657550 | 2019 | MiR-32-5p regulates the proliferation and metastasis of cervical cancer cells by targeting HOXB8. | 19 |
| 30677006 | 2019 | Knock-Down of HOXB8 Prohibits Proliferation and Migration of Colorectal Cancer Cells via Wnt/β-Catenin Signaling Pathway. | 10 |
| 30954562 | 2019 | Knockdown of HOXB8 inhibits tumor growth and metastasis by the inactivation of Wnt/β-catenin signaling pathway in osteosarcoma. | 9 |
Citation
Dessen P
HOXB8 (homeobox B8)
Atlas Genet Cytogenet Oncol Haematol. 2013-07-01
Online version: http://atlasgeneticsoncology.org/gene/53424/hoxb8-(homeobox-b8)
