PON3 (paraoxonase 3)

2013-07-01  

Identity

HGNC
LOCATION
7q21.3
LOCUSID
ALIAS
-

Other Information

Locus ID:

NCBI: 5446
MIM: 602720
HGNC: 9206
Ensembl: ENSG00000105852

Variants:

dbSNP: 5446
ClinVar: 5446
TCGA: ENSG00000105852
COSMIC: PON3

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000105852ENST00000265627Q15166
ENSG00000105852ENST00000418617F2Z2L3
ENSG00000105852ENST00000427422C9JZ99
ENSG00000105852ENST00000442770F2Z2L3
ENSG00000105852ENST00000451904F8WD41
ENSG00000105852ENST00000456855F8WBV4

Expression (GTEx)

0
50
100
150

Pathways

PathwaySourceExternal ID
Metabolic pathwaysKEGGhsa01100
MetabolismREACTOMER-HSA-1430728
Metabolism of lipids and lipoproteinsREACTOMER-HSA-556833
Arachidonic acid metabolismREACTOMER-HSA-2142753
Synthesis of 5-eicosatetraenoic acidsREACTOMER-HSA-2142688

Protein levels (Protein atlas)

Not detected
Low
Medium
High

References

Pubmed IDYearTitleCitations
331282472021Micro- and macrovascular cardiac allograft vasculopathy in relation to 91 cardiovascular biomarkers in heart transplant recipients-An exploratory study.1
331282472021Micro- and macrovascular cardiac allograft vasculopathy in relation to 91 cardiovascular biomarkers in heart transplant recipients-An exploratory study.1
325495222020Serum paraoxonase 1 and 3 activities in benign and malignant diseases of the prostate and changes in levels following robotic-assisted laparoscopic radical prostatectomy.4
330573862020Paraoxonase 3 gene polymorphisms are associated with occupational noise-induced deafness: A matched case-control study from China.3
325495222020Serum paraoxonase 1 and 3 activities in benign and malignant diseases of the prostate and changes in levels following robotic-assisted laparoscopic radical prostatectomy.4
330573862020Paraoxonase 3 gene polymorphisms are associated with occupational noise-induced deafness: A matched case-control study from China.3
285095262019Paraoxonases and psoriasis: negative imbalance of antioxidant endogenous mechanisms.3
309774472019PON1 Hypermethylation and PON3 Hypomethylation are Associated with Risk of Cerebral Infarction.6
318168462019Paraoxonase 3: Structure and Its Role in Pathophysiology of Coronary Artery Disease.14
285095262019Paraoxonases and psoriasis: negative imbalance of antioxidant endogenous mechanisms.3
309774472019PON1 Hypermethylation and PON3 Hypomethylation are Associated with Risk of Cerebral Infarction.6
318168462019Paraoxonase 3: Structure and Its Role in Pathophysiology of Coronary Artery Disease.14
277713682017Paraoxonase and atherosclerosis-related cardiovascular diseases.54
279236882017Paraoxonase 3 promotes cell proliferation and metastasis by PI3K/Akt in oral squamous cell carcinoma.7
284336102017Paraoxonases and infectious diseases.21

Citation

Dessen P

PON3 (paraoxonase 3)

Atlas Genet Cytogenet Oncol Haematol. 2013-07-01

Online version: http://atlasgeneticsoncology.org/gene/53436/pon3-(paraoxonase-3)