EOMES (eomesodermin)

2013-07-01  

Identity

HGNC
LOCATION
3p24.1
LOCUSID
ALIAS
TBR2
FUSION GENES

Other Information

Locus ID:

NCBI: 8320
MIM: 604615
HGNC: 3372
Ensembl: ENSG00000163508

Variants:

dbSNP: 8320
ClinVar: 8320
TCGA: ENSG00000163508
COSMIC: EOMES

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000163508ENST00000295743O95936
ENSG00000163508ENST00000449599O95936
ENSG00000163508ENST00000461503O95936

Expression (GTEx)

0
5
10
15
20
25
30

Protein levels (Protein atlas)

Not detected
Low
Medium
High

References

Pubmed IDYearTitleCitations
381897792024Eomes-dependent mitochondrial regulation promotes survival of pathogenic CD4+ T cells during inflammation.2
381897792024Eomes-dependent mitochondrial regulation promotes survival of pathogenic CD4+ T cells during inflammation.2
372790782023T-BET and EOMES sustain mature human NK cell identity and antitumor function.5
372790782023T-BET and EOMES sustain mature human NK cell identity and antitumor function.5
349865102022The transcription factor Eomes promotes expression of inhibitory receptors on hepatic CD8(+) T cells during HBV persistence.2
357341622022Transcriptional Pattern Analysis of Virus-Specific CD8+ T Cells in Hepatitis C Infection: Increased Expression of TOX and Eomesodermin During and After Persistent Antigen Recognition.4
349865102022The transcription factor Eomes promotes expression of inhibitory receptors on hepatic CD8(+) T cells during HBV persistence.2
357341622022Transcriptional Pattern Analysis of Virus-Specific CD8+ T Cells in Hepatitis C Infection: Increased Expression of TOX and Eomesodermin During and After Persistent Antigen Recognition.4
328308982021Characterization of KIR + NKG2A + Eomes- NK-like CD8+ T cells and their decline with age in healthy individuals.6
331132662021Eomes promotes esophageal carcinoma progression by recruiting Treg cells through the CCL20-CCR6 pathway.17
333256362021Down-regulation of EOMES drives T-cell exhaustion via abolishing EOMES-mediated repression of inhibitory receptors of T cells in liver cancer.8
336373232021Eomesodermin regulate decidual CD4(+)T cell function during human early pregnancy.3
337318482021EOMES is essential for antitumor activity of CD8(+) T cells in chronic lymphocytic leukemia.19
338365942021Involvement of cytotoxic Eomes-expressing CD4(+) T cells in secondary progressive multiple sclerosis.32
339721812021Impact of mTOR signaling pathway on CD8+ T cell immunity through Eomesodermin in response to invasive candidiasis.2

Citation

Dessen P

EOMES (eomesodermin)

Atlas Genet Cytogenet Oncol Haematol. 2013-07-01

Online version: http://atlasgeneticsoncology.org/gene/53445/