Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, contribute in submission tool
Other Information
Locus ID:
NCBI: 23007
MIM: 612835
HGNC: 29185
Ensembl: ENSG00000114805
Variants:
dbSNP: 23007
ClinVar: 23007
TCGA: ENSG00000114805
COSMIC: PLCH1
RNA/Proteins
Expression (GTEx)
Pathways
Protein levels (Protein atlas)
PharmGKB
| Entity ID | Name | Type | Evidence | Association | PK | PD | PMIDs |
|---|---|---|---|---|---|---|---|
| PA26097 | CASR | Gene | Pathway | associated | |||
| PA33759 | PRKCA | Gene | Pathway | associated | |||
| PA33761 | PRKCB | Gene | Pathway | associated | |||
| PA33766 | PRKCG | Gene | Pathway | associated | |||
| PA33767 | PRKCH | Gene | Pathway | associated | |||
| PA33768 | PRKCI | Gene | Pathway | associated | |||
| PA33771 | PRKD1 | Gene | Pathway | associated | |||
| PA33775 | PRKCZ | Gene | Pathway | associated |
References
| Pubmed ID | Year | Title | Citations |
|---|---|---|---|
| 33820834 | 2022 | Mutations in phospholipase C eta-1 (PLCH1) are associated with holoprosencephaly. | 1 |
| 33820834 | 2022 | Mutations in phospholipase C eta-1 (PLCH1) are associated with holoprosencephaly. | 1 |
| 27089467 | 2016 | Expression profile of PLCζ, PAWP, and TR-KIT in association with fertilization potential, embryo development, and pregnancy outcomes in globozoospermic candidates for intra-cytoplasmic sperm injection and artificial oocyte activation. | 19 |
| 27089467 | 2016 | Expression profile of PLCζ, PAWP, and TR-KIT in association with fertilization potential, embryo development, and pregnancy outcomes in globozoospermic candidates for intra-cytoplasmic sperm injection and artificial oocyte activation. | 19 |
| 24123053 | 2014 | A canonical EF-loop directs Ca(2+) -sensitivity in phospholipase C-η2. | 6 |
| 24123053 | 2014 | A canonical EF-loop directs Ca(2+) -sensitivity in phospholipase C-η2. | 6 |
| 22658813 | 2013 | Association between polymorphisms in COMT, PLCH1, and CYP17A1, and non-small-cell lung cancer risk in Chinese nonsmokers. | 12 |
| 22658813 | 2013 | Association between polymorphisms in COMT, PLCH1, and CYP17A1, and non-small-cell lung cancer risk in Chinese nonsmokers. | 12 |
| 20628086 | 2010 | Variation at the NFATC2 locus increases the risk of thiazolidinedione-induced edema in the Diabetes REduction Assessment with ramipril and rosiglitazone Medication (DREAM) study. | 15 |
| 20628086 | 2010 | Variation at the NFATC2 locus increases the risk of thiazolidinedione-induced edema in the Diabetes REduction Assessment with ramipril and rosiglitazone Medication (DREAM) study. | 15 |
| 19913121 | 2009 | Gene-centric association signals for lipids and apolipoproteins identified via the HumanCVD BeadChip. | 105 |
| 19913121 | 2009 | Gene-centric association signals for lipids and apolipoproteins identified via the HumanCVD BeadChip. | 105 |
| 15583837 | 2005 | Identification of a novel class of mammalian phosphoinositol-specific phospholipase C enzymes. | 14 |
| 15702972 | 2005 | Molecular cloning and characterization of a novel phospholipase C, PLC-eta. | 30 |
| 15583837 | 2005 | Identification of a novel class of mammalian phosphoinositol-specific phospholipase C enzymes. | 14 |
Citation
Dessen P
PLCH1 (phospholipase C eta 1)
Atlas Genet Cytogenet Oncol Haematol. 2013-07-01
Online version: http://atlasgeneticsoncology.org/gene/53447/plch1-(phospholipase-c-eta-1)
