Identity
HGNC
LOCATION
18q11.2
LOCUSID
ALIAS
HsT2456,SMD1,SNRPD,Sm-D1
FUSION GENES
Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, contribute in submission tool
Other Information
Locus ID:
NCBI: 6632
MIM: 601063
HGNC: 11158
Ensembl: ENSG00000167088
Variants:
dbSNP: 6632
ClinVar: 6632
TCGA: ENSG00000167088
COSMIC: SNRPD1
RNA/Proteins
| Gene ID | Transcript ID | Uniprot |
|---|---|---|
| ENSG00000167088 | ENST00000300413 | P62314 |
| ENSG00000167088 | ENST00000579618 | J3QLR7 |
| ENSG00000167088 | ENST00000582475 | J3QLI9 |
Expression (GTEx)
Pathways
Protein levels (Protein atlas)
References
| Pubmed ID | Year | Title | Citations |
|---|---|---|---|
| 37268273 | 2023 | SNRPD1 inhibition suppresses the proliferation of hepatocellular carcinoma and promotes autophagy through the PI3K/AKT/mTOR/4EBP1 pathway. | 4 |
| 37268273 | 2023 | SNRPD1 inhibition suppresses the proliferation of hepatocellular carcinoma and promotes autophagy through the PI3K/AKT/mTOR/4EBP1 pathway. | 4 |
| 28595116 | 2017 | The unique spliceosome signature of human pluripotent stem cells is mediated by SNRPA1, SNRPD1, and PNN. | 20 |
| 28790444 | 2017 | Anti-SmD1 antibodies are associated with renal disorder, seizures, and pulmonary arterial hypertension in Chinese patients with active SLE. | 8 |
| 28595116 | 2017 | The unique spliceosome signature of human pluripotent stem cells is mediated by SNRPA1, SNRPD1, and PNN. | 20 |
| 28790444 | 2017 | Anti-SmD1 antibodies are associated with renal disorder, seizures, and pulmonary arterial hypertension in Chinese patients with active SLE. | 8 |
| 24413165 | 2014 | The SMN Tudor SIM-like domain is key to SmD1 and coilin interactions and to Cajal body biogenesis. | 13 |
| 25273532 | 2014 | Association of cerebrospinal fluid anti-Sm antibodies with acute confusional state in systemic lupus erythematosus. | 24 |
| 24413165 | 2014 | The SMN Tudor SIM-like domain is key to SmD1 and coilin interactions and to Cajal body biogenesis. | 13 |
| 25273532 | 2014 | Association of cerebrospinal fluid anti-Sm antibodies with acute confusional state in systemic lupus erythematosus. | 24 |
| 23358685 | 2013 | Targeting the deregulated spliceosome core machinery in cancer cells triggers mTOR blockade and autophagy. | 51 |
| 23358685 | 2013 | Targeting the deregulated spliceosome core machinery in cancer cells triggers mTOR blockade and autophagy. | 51 |
Citation
Dessen P
SNRPD1 (small nuclear ribonucleoprotein D1 polypeptide)
Atlas Genet Cytogenet Oncol Haematol. 2013-07-01
Online version: http://atlasgeneticsoncology.org/gene/53452/snrpd1-(small-nuclear-ribonucleoprotein-d1-polypeptide)
