Identity
HGNC
LOCATION
16q23.1
LOCUSID
ALIAS
ATG8,ATG8C,GATE-16,GATE16,GEF-2,GEF2
FUSION GENES
Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, contribute in submission tool
Other Information
Locus ID:
NCBI: 11345
MIM: 607452
HGNC: 13291
Ensembl: ENSG00000034713
Variants:
dbSNP: 11345
ClinVar: 11345
TCGA: ENSG00000034713
COSMIC: GABARAPL2
RNA/Proteins
| Gene ID | Transcript ID | Uniprot |
|---|---|---|
| ENSG00000034713 | ENST00000037243 | P60520 |
| ENSG00000034713 | ENST00000563744 | H3BU36 |
| ENSG00000034713 | ENST00000565057 | H3BSM5 |
| ENSG00000034713 | ENST00000568455 | H3BQ50 |
Expression (GTEx)
Pathways
Protein levels (Protein atlas)
References
| Pubmed ID | Year | Title | Citations |
|---|---|---|---|
| 37312406 | 2024 | ATG8 proteins are co-factors for human dopaminergic neuronal transcriptional control: implications for neuronal resilience in Parkinson disease. | 1 |
| 37312406 | 2024 | ATG8 proteins are co-factors for human dopaminergic neuronal transcriptional control: implications for neuronal resilience in Parkinson disease. | 1 |
| 34929165 | 2022 | An ALS-associated variant of the autophagy receptor SQSTM1/p62 reprograms binding selectivity toward the autophagy-related hATG8 proteins. | 3 |
| 35258397 | 2022 | The V-ATPase complex regulates non-canonical Atg8-family protein lipidation through ATG16L1 recruitment. | 1 |
| 34929165 | 2022 | An ALS-associated variant of the autophagy receptor SQSTM1/p62 reprograms binding selectivity toward the autophagy-related hATG8 proteins. | 3 |
| 35258397 | 2022 | The V-ATPase complex regulates non-canonical Atg8-family protein lipidation through ATG16L1 recruitment. | 1 |
| 33845085 | 2021 | Phosphorylation of the LIR Domain of SCOC Modulates ATG8 Binding Affinity and Specificity. | 10 |
| 33909989 | 2021 | Non-canonical autophagy drives alternative ATG8 conjugation to phosphatidylserine. | 65 |
| 33845085 | 2021 | Phosphorylation of the LIR Domain of SCOC Modulates ATG8 Binding Affinity and Specificity. | 10 |
| 33909989 | 2021 | Non-canonical autophagy drives alternative ATG8 conjugation to phosphatidylserine. | 65 |
| 30990354 | 2020 | An atypical LIR motif within UBA5 (ubiquitin like modifier activating enzyme 5) interacts with GABARAP proteins and mediates membrane localization of UBA5. | 23 |
| 31960529 | 2020 | Curvature-sensitive trans-assembly of human Atg8-family proteins in autophagy-related membrane tethering. | 10 |
| 32094251 | 2020 | GABARAPL2 Is Critical for Growth Restriction of Toxoplasma gondii in HeLa Cells Treated with Gamma Interferon. | 11 |
| 32437499 | 2020 | A PI3K-WIPI2 positive feedback loop allosterically activates LC3 lipidation in autophagy. | 46 |
| 32685442 | 2020 | Autophagic Network Analysis of the Dual Effect of Sevoflurane on Neurons Associated with GABARAPL1 and 2. | 3 |
Citation
Dessen P
GABARAPL2 (GABA type A receptor associated protein like 2)
Atlas Genet Cytogenet Oncol Haematol. 2013-07-01
Online version: http://atlasgeneticsoncology.org/gene/53460/
