BAIAP2L1 (BAR/IMD domain containing adaptor protein 2 like 1)

2013-07-01  

Identity

HGNC
LOCATION
7q21.3
LOCUSID
ALIAS
IRTKS
FUSION GENES

Other Information

Locus ID:

NCBI: 55971
MIM: 611877
HGNC: 21649
Ensembl: ENSG00000006453

Variants:

dbSNP: 55971
ClinVar: 55971
TCGA: ENSG00000006453
COSMIC: BAIAP2L1

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000006453ENST00000005260Q9UHR4

Expression (GTEx)

0
10
20
30
40
50
60

Protein levels (Protein atlas)

Not detected
Low
Medium
High

References

Pubmed IDYearTitleCitations
388697212024IRTKS contributes to the malignant progression of cervical cancer cells.0
388697212024IRTKS contributes to the malignant progression of cervical cancer cells.0
363080672023BAIAP2L1 accelerates breast cancer progression and chemoresistance by activating AKT signaling through binding with ribosomal protein L3.5
363080672023BAIAP2L1 accelerates breast cancer progression and chemoresistance by activating AKT signaling through binding with ribosomal protein L3.5
348119392022BAIAP2L1 enables cancer cell migration and facilitates phospho-Cofilin asymmetry localization in the border cells.3
360570382022Insulin receptor tyrosine kinase substrate (IRTKS) promotes the tumorigenesis of pancreatic cancer via PI3K/AKT signaling.2
348119392022BAIAP2L1 enables cancer cell migration and facilitates phospho-Cofilin asymmetry localization in the border cells.3
360570382022Insulin receptor tyrosine kinase substrate (IRTKS) promotes the tumorigenesis of pancreatic cancer via PI3K/AKT signaling.2
301970892018IRTKS (BAIAP2L1) Elongates Epithelial Microvilli Using EPS8-Dependent and Independent Mechanisms.29
301970892018IRTKS (BAIAP2L1) Elongates Epithelial Microvilli Using EPS8-Dependent and Independent Mechanisms.29
272780192016The Rho GTPase Rif signals through IRTKS, Eps8 and WAVE2 to generate dorsal membrane ruffles and filopodia.12
276937832016The SH3 domain distinguishes the role of I-BAR proteins IRTKS and MIM in chemotactic response to serum.5
272780192016The Rho GTPase Rif signals through IRTKS, Eps8 and WAVE2 to generate dorsal membrane ruffles and filopodia.12
276937832016The SH3 domain distinguishes the role of I-BAR proteins IRTKS and MIM in chemotactic response to serum.5
255894962015Mechanism of Oncogenic Signal Activation by the Novel Fusion Kinase FGFR3-BAIAP2L1.25

Citation

Dessen P

BAIAP2L1 (BAR/IMD domain containing adaptor protein 2 like 1)

Atlas Genet Cytogenet Oncol Haematol. 2013-07-01

Online version: http://atlasgeneticsoncology.org/gene/53465/baiap2l1-(bar-imd-domain-containing-adaptor-protein-2-like-1)