Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, contribute in submission tool
Other Information
Locus ID:
NCBI: 25797
MIM: 607065
HGNC: 9753
Ensembl: ENSG00000115828
Variants:
dbSNP: 25797
ClinVar: 25797
TCGA: ENSG00000115828
COSMIC: QPCT
RNA/Proteins
| Gene ID | Transcript ID | Uniprot |
|---|---|---|
| ENSG00000115828 | ENST00000338415 | Q16769 |
| ENSG00000115828 | ENST00000404976 | B5MCZ9 |
| ENSG00000115828 | ENST00000444022 | C9JS14 |
| ENSG00000115828 | ENST00000650442 | A0A3B3IUD5 |
Expression (GTEx)
Pathways
| Pathway | Source | External ID |
|---|---|---|
| Immune System | REACTOME | R-HSA-168256 |
| Innate Immune System | REACTOME | R-HSA-168249 |
| Neutrophil degranulation | REACTOME | R-HSA-6798695 |
Protein levels (Protein atlas)
References
| Pubmed ID | Year | Title | Citations |
|---|---|---|---|
| 37060824 | 2023 | Clinical significance and diagnostic value of QPCT, SCEL and TNFRSF12A in papillary thyroid cancer. | 3 |
| 37381175 | 2023 | Apicidin confers promising therapeutic effect on acute myeloid leukemia cells via increasing QPCT expression. | 1 |
| 37060824 | 2023 | Clinical significance and diagnostic value of QPCT, SCEL and TNFRSF12A in papillary thyroid cancer. | 3 |
| 37381175 | 2023 | Apicidin confers promising therapeutic effect on acute myeloid leukemia cells via increasing QPCT expression. | 1 |
| 33774034 | 2021 | A Unique Carboxylic-Acid Hydrogen-Bond Network (CAHBN) Confers Glutaminyl Cyclase Activity on M28 Family Enzymes. | 1 |
| 34036385 | 2021 | QPCT regulation by CTCF leads to sunitinib resistance in renal cell carcinoma by promoting angiogenesis. | 4 |
| 34309760 | 2021 | A glutaminyl cyclase-catalyzed α-synuclein modification identified in human synucleinopathies. | 8 |
| 33774034 | 2021 | A Unique Carboxylic-Acid Hydrogen-Bond Network (CAHBN) Confers Glutaminyl Cyclase Activity on M28 Family Enzymes. | 1 |
| 34036385 | 2021 | QPCT regulation by CTCF leads to sunitinib resistance in renal cell carcinoma by promoting angiogenesis. | 4 |
| 34309760 | 2021 | A glutaminyl cyclase-catalyzed α-synuclein modification identified in human synucleinopathies. | 8 |
| 32551535 | 2020 | Hydrazides Are Potent Transition-State Analogues for Glutaminyl Cyclase Implicated in the Pathogenesis of Alzheimer's Disease. | 3 |
| 32551535 | 2020 | Hydrazides Are Potent Transition-State Analogues for Glutaminyl Cyclase Implicated in the Pathogenesis of Alzheimer's Disease. | 3 |
| 28587659 | 2017 | Glutaminyl cyclase activity correlates with levels of Aβ peptides and mediators of angiogenesis in cerebrospinal fluid of Alzheimer's disease patients. | 7 |
| 28587659 | 2017 | Glutaminyl cyclase activity correlates with levels of Aβ peptides and mediators of angiogenesis in cerebrospinal fluid of Alzheimer's disease patients. | 7 |
| 26492838 | 2016 | Common variants in QPCT gene confer risk of schizophrenia in the Han Chinese population. | 2 |
Citation
Dessen P
QPCT (glutaminyl-peptide cyclotransferase)
Atlas Genet Cytogenet Oncol Haematol. 2013-07-01
Online version: http://atlasgeneticsoncology.org/gene/53467/qpct-(glutaminyl-peptide-cyclotransferase)
