FAM189B (family with sequence similarity 189 member B)

2013-07-01  

Identity

HGNC
LOCATION
1q22
LOCUSID
ALIAS
C1orf2,COTE1
FUSION GENES

Other Information

Locus ID:

NCBI: 10712
HGNC: 1233
Ensembl: ENSG00000160767

Variants:

dbSNP: 10712
ClinVar: 10712
TCGA: ENSG00000160767
COSMIC: FAM189B

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000160767ENST00000350210P81408
ENSG00000160767ENST00000361361P81408
ENSG00000160767ENST00000368368P81408
ENSG00000160767ENST00000487649Q96AD8
ENSG00000160767ENST00000491082D6RD59
ENSG00000160767ENST00000621094Q96H71

Expression (GTEx)

0
5
10
15
20
25
30
35
40
45
50

Protein levels (Protein atlas)

Not detected
Low
Medium
High

References

Pubmed IDYearTitleCitations
374548762023COTE-1 promotes the proliferation and invasion of small cell lung cancer by regulating autophagy activity via the AMPK/mTOR signaling pathway.1
377804852023COTE1 Facilitates Intrahepatic Cholangiocarcinoma Progression via Beclin1-Dependent Autophagy Inhibition.0
374548762023COTE-1 promotes the proliferation and invasion of small cell lung cancer by regulating autophagy activity via the AMPK/mTOR signaling pathway.1
377804852023COTE1 Facilitates Intrahepatic Cholangiocarcinoma Progression via Beclin1-Dependent Autophagy Inhibition.0
341242642021High FAM189B Expression and Its Prognostic Value in Patients with Gastric Cancer.1
341242642021High FAM189B Expression and Its Prognostic Value in Patients with Gastric Cancer.1
248994072014Upregulation of the putative oncogene COTE1 contributes to human hepatocarcinogenesis through modulation of WWOX signaling.4
248994072014Upregulation of the putative oncogene COTE1 contributes to human hepatocarcinogenesis through modulation of WWOX signaling.4
233172592012Ectopic overexpression of COTE1 promotes cellular invasion of hepatocellular carcinoma.7
233172592012Ectopic overexpression of COTE1 promotes cellular invasion of hepatocellular carcinoma.7

Citation

Dessen P

FAM189B (family with sequence similarity 189 member B)

Atlas Genet Cytogenet Oncol Haematol. 2013-07-01

Online version: http://atlasgeneticsoncology.org/gene/53469/fam189b-(family-with-sequence-similarity-189-member-b)