SPATA22 (spermatogenesis associated 22)

2013-07-01  

Identity

HGNC
LOCATION
17p13.2
LOCUSID
ALIAS
NYD-SP20,NYDSP20
FUSION GENES

Other Information

Locus ID:

NCBI: 84690
MIM: 617673
HGNC: 30705
Ensembl: ENSG00000141255

Variants:

dbSNP: 84690
ClinVar: 84690
TCGA: ENSG00000141255
COSMIC: SPATA22

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000141255ENST00000268981Q8NHS9
ENSG00000141255ENST00000355380Q8NHS9
ENSG00000141255ENST00000397168Q8NHS9
ENSG00000141255ENST00000397168A0A140VJV9
ENSG00000141255ENST00000541913F5GWB9
ENSG00000141255ENST00000571553I3L2B9
ENSG00000141255ENST00000571607I3L1L5
ENSG00000141255ENST00000572582I3L4D7
ENSG00000141255ENST00000572969Q8NHS9
ENSG00000141255ENST00000572969A0A140VJV9
ENSG00000141255ENST00000573128Q8NHS9
ENSG00000141255ENST00000573128A0A140VJV9
ENSG00000141255ENST00000574051I3L4R7
ENSG00000141255ENST00000574457I3L3S6
ENSG00000141255ENST00000574797I3L517
ENSG00000141255ENST00000575375Q8NHS9
ENSG00000141255ENST00000575375A0A140VJV9

Expression (GTEx)

0
50
100
150
200

References

Pubmed IDYearTitleCitations
352850202022Bi-allelic SPATA22 variants cause premature ovarian insufficiency and nonobstructive azoospermia due to meiotic arrest.5
363312992022Nuclear localization of human MEIOB requires its NLS in the OB domain and interaction with SPATA22.0
352850202022Bi-allelic SPATA22 variants cause premature ovarian insufficiency and nonobstructive azoospermia due to meiotic arrest.5
363312992022Nuclear localization of human MEIOB requires its NLS in the OB domain and interaction with SPATA22.0
338122312021The meiosis-specific MEIOB-SPATA22 complex cooperates with RPA to form a compacted mixed MEIOB/SPATA22/RPA/ssDNA complex.9
343923562021Whole-exome sequencing of consanguineous families with infertile men and women identifies homologous mutations in SPATA22 and MEIOB.14
338122312021The meiosis-specific MEIOB-SPATA22 complex cooperates with RPA to form a compacted mixed MEIOB/SPATA22/RPA/ssDNA complex.9
343923562021Whole-exome sequencing of consanguineous families with infertile men and women identifies homologous mutations in SPATA22 and MEIOB.14
236759072013Expression analysis of MND1/GAJ, SPATA22, GAPDHS and ACR genes in testicular biopsies from non-obstructive azoospermia (NOA) patients.10
236759072013Expression analysis of MND1/GAJ, SPATA22, GAPDHS and ACR genes in testicular biopsies from non-obstructive azoospermia (NOA) patients.10
203786152010Evaluation of 172 candidate polymorphisms for association with oligozoospermia or azoospermia in a large cohort of men of European descent.61
203786152010Evaluation of 172 candidate polymorphisms for association with oligozoospermia or azoospermia in a large cohort of men of European descent.61

Citation

Dessen P

SPATA22 (spermatogenesis associated 22)

Atlas Genet Cytogenet Oncol Haematol. 2013-07-01

Online version: http://atlasgeneticsoncology.org/gene/53472/spata22-(spermatogenesis-associated-22)