CHST15 (carbohydrate sulfotransferase 15)

2013-08-01  

Identity

HGNC
LOCATION
10q26.13
LOCUSID
ALIAS
BRAG,GALNAC4S-6ST
FUSION GENES

Other Information

Locus ID:

NCBI: 51363
MIM: 608277
HGNC: 18137
Ensembl: ENSG00000182022

Variants:

dbSNP: 51363
ClinVar: 51363
TCGA: ENSG00000182022
COSMIC: CHST15

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000182022ENST00000346248Q7LFX5
ENSG00000182022ENST00000435907Q7LFX5
ENSG00000182022ENST00000462406A0A0D9SFZ3
ENSG00000182022ENST00000628426Q7LFX5

Expression (GTEx)

0
10
20
30
40
50
60
70

Pathways

PathwaySourceExternal ID
Glycosaminoglycan biosynthesis - chondroitin sulfate / dermatan sulfateKEGGko00532
Glycosaminoglycan biosynthesis - chondroitin sulfate / dermatan sulfateKEGGhsa00532
MetabolismREACTOMER-HSA-1430728
Metabolism of carbohydratesREACTOMER-HSA-71387
Glycosaminoglycan metabolismREACTOMER-HSA-1630316
Chondroitin sulfate/dermatan sulfate metabolismREACTOMER-HSA-1793185
Chondroitin sulfate biosynthesisREACTOMER-HSA-2022870

Protein levels (Protein atlas)

Not detected
Low
Medium
High

References

Pubmed IDYearTitleCitations
163854512006A scan of chromosome 10 identifies a novel locus showing strong association with late-onset Alzheimer disease.69
309635682019Long noncoding RNA HOTAIR promotes invasion of breast cancer cells through chondroitin sulfotransferase CHST15.11
266423492015Inhibition of Cell Proliferation and Growth of Pancreatic Cancer by Silencing of Carbohydrate Sulfotransferase 15 In Vitro and in a Xenograft Model.9
274106852016Pivotal Role of Carbohydrate Sulfotransferase 15 in Fibrosis and Mucosal Healing in Mouse Colitis.8
233498462013Role of GalNAc4S-6ST in astrocytic tumor progression.6
317464002020CHST15 promotes the proliferation of TE‑1 cells via multiple pathways in esophageal cancer.0

Citation

Dessen P

CHST15 (carbohydrate sulfotransferase 15)

Atlas Genet Cytogenet Oncol Haematol. 2013-08-01

Online version: http://atlasgeneticsoncology.org/gene/53475/chst15-(carbohydrate-sulfotransferase-15)