Identity
HGNC
LOCATION
21q21.3
LOCUSID
ALIAS
C21orf43,CD322,IBGC8,JAM-B,JAMB,PRO245,VE-JAM,VEJAM
FUSION GENES
Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, contribute in submission tool
Other Information
Locus ID:
NCBI: 58494
MIM: 606870
HGNC: 14686
Ensembl: ENSG00000154721
Variants:
dbSNP: 58494
ClinVar: 58494
TCGA: ENSG00000154721
COSMIC: JAM2
RNA/Proteins
| Gene ID | Transcript ID | Uniprot |
|---|---|---|
| ENSG00000154721 | ENST00000312957 | P57087 |
| ENSG00000154721 | ENST00000400532 | P57087 |
| ENSG00000154721 | ENST00000460679 | H0YEX9 |
| ENSG00000154721 | ENST00000480456 | P57087 |
Expression (GTEx)
Pathways
References
| Pubmed ID | Year | Title | Citations |
|---|---|---|---|
| 38404047 | 2024 | JAM2 is a prognostic biomarker and inhibits proliferation, metastasis and epithelial-mesenchymal transition in lung adenocarcinoma. | 0 |
| 38404047 | 2024 | JAM2 is a prognostic biomarker and inhibits proliferation, metastasis and epithelial-mesenchymal transition in lung adenocarcinoma. | 0 |
| 34923424 | 2022 | JAM2 predicts a good prognosis and inhibits invasion and migration by suppressing EMT pathway in breast cancer. | 6 |
| 34923424 | 2022 | JAM2 predicts a good prognosis and inhibits invasion and migration by suppressing EMT pathway in breast cancer. | 6 |
| 31851307 | 2020 | Biallelic loss-of-function mutations in JAM2 cause primary familial brain calcification. | 36 |
| 32142645 | 2020 | Bi-allelic JAM2 Variants Lead to Early-Onset Recessive Primary Familial Brain Calcification. | 33 |
| 31851307 | 2020 | Biallelic loss-of-function mutations in JAM2 cause primary familial brain calcification. | 36 |
| 32142645 | 2020 | Bi-allelic JAM2 Variants Lead to Early-Onset Recessive Primary Familial Brain Calcification. | 33 |
| 29575013 | 2018 | MicroRNA-374b inhibits cervical cancer cell proliferation and induces apoptosis through the p38/ERK signaling pathway by binding to JAM-2. | 19 |
| 29575013 | 2018 | MicroRNA-374b inhibits cervical cancer cell proliferation and induces apoptosis through the p38/ERK signaling pathway by binding to JAM-2. | 19 |
| 26782073 | 2016 | Effect of junctional adhesion molecule-2 expression on cell growth, invasion and migration in human colorectal cancer. | 14 |
| 27121546 | 2016 | The role of JAM-B in cancer and cancer metastasis (Review). | 8 |
| 26782073 | 2016 | Effect of junctional adhesion molecule-2 expression on cell growth, invasion and migration in human colorectal cancer. | 14 |
| 27121546 | 2016 | The role of JAM-B in cancer and cancer metastasis (Review). | 8 |
| 25649652 | 2015 | Linking Genetics of Brain Changes to Alzheimer's Disease: Sparse Whole Genome Association Scan of Regional MRI Volumes in the ADNI and AddNeuroMed Cohorts. | 8 |
Citation
Dessen P
JAM2 (junctional adhesion molecule 2)
Atlas Genet Cytogenet Oncol Haematol. 2013-08-01
Online version: http://atlasgeneticsoncology.org/gene/53483/jam2-(junctional-adhesion-molecule-2)
