WDR26 (WD repeat domain 26)

2013-09-01  

Identity

HGNC
LOCATION
1q42.11
LOCUSID
ALIAS
CDW2,GID7,MIP2,SKDEAS
FUSION GENES

Other Information

Locus ID:

NCBI: 80232
MIM: 617424
HGNC: 21208
Ensembl: ENSG00000162923

Variants:

dbSNP: 80232
ClinVar: 80232
TCGA: ENSG00000162923
COSMIC: WDR26

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000162923ENST00000414423A0A499FIZ0
ENSG00000162923ENST00000445239C9JCS7
ENSG00000162923ENST00000480676H0Y9R3
ENSG00000162923ENST00000486652H0Y917
ENSG00000162923ENST00000651911Q9H7D7

Expression (GTEx)

0
10
20
30
40
50
60
70
80

Protein levels (Protein atlas)

Not detected
Low
Medium
High

References

Pubmed IDYearTitleCitations
385755272024Skraban-Deardorff intellectual disability syndrome-associated mutations in WDR26 impair CTLH E3 complex assembly.1
385755272024Skraban-Deardorff intellectual disability syndrome-associated mutations in WDR26 impair CTLH E3 complex assembly.1
356271972022Two Novel Variants of WDR26 in Chinese Patients with Intellectual Disability.0
356271972022Two Novel Variants of WDR26 in Chinese Patients with Intellectual Disability.0
335065102021Skraban-Deardorff syndrome: Six new cases of WDR26-related disease and expansion of the clinical phenotype.2
336752732021Expanding the clinical phenotype of the ultra-rare Skraban-Deardorff syndrome: Two novel individuals with WDR26 loss-of-function variants and a literature review.2
339056822021GID E3 ligase supramolecular chelate assembly configures multipronged ubiquitin targeting of an oligomeric metabolic enzyme.27
335065102021Skraban-Deardorff syndrome: Six new cases of WDR26-related disease and expansion of the clinical phenotype.2
336752732021Expanding the clinical phenotype of the ultra-rare Skraban-Deardorff syndrome: Two novel individuals with WDR26 loss-of-function variants and a literature review.2
339056822021GID E3 ligase supramolecular chelate assembly configures multipronged ubiquitin targeting of an oligomeric metabolic enzyme.27
329581402020WD40 Repeat Protein 26 Negatively Regulates Formyl Peptide Receptor-1 Mediated Wound Healing in Intestinal Epithelial Cells.1
329581402020WD40 Repeat Protein 26 Negatively Regulates Formyl Peptide Receptor-1 Mediated Wound Healing in Intestinal Epithelial Cells.1
286868532017WDR26 Haploinsufficiency Causes a Recognizable Syndrome of Intellectual Disability, Seizures, Abnormal Gait, and Distinctive Facial Features.20
286868532017WDR26 Haploinsufficiency Causes a Recognizable Syndrome of Intellectual Disability, Seizures, Abnormal Gait, and Distinctive Facial Features.20
268953802016Upregulated WDR26 serves as a scaffold to coordinate PI3K/ AKT pathway-driven breast cancer cell growth, migration, and invasion.30

Citation

Dessen P

WDR26 (WD repeat domain 26)

Atlas Genet Cytogenet Oncol Haematol. 2013-09-01

Online version: http://atlasgeneticsoncology.org/gene/53496/wdr26-(wd-repeat-domain-26)