Identity
HGNC
LOCATION
5q22.3
LOCUSID
ALIAS
APG12,APG12L,FBR93,HAPG12
FUSION GENES
Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, contribute in submission tool
Other Information
Locus ID:
NCBI: 9140
MIM: 609608
HGNC: 588
Ensembl: ENSG00000145782
Variants:
dbSNP: 9140
ClinVar: 9140
TCGA: ENSG00000145782
COSMIC: ATG12
RNA/Proteins
Expression (GTEx)
Pathways
Protein levels (Protein atlas)
References
| Pubmed ID | Year | Title | Citations |
|---|---|---|---|
| 37866664 | 2024 | circ_SIRT1 upregulates ATG12 to facilitate Imatinib resistance in CML through interacting with EIF4A3. | 0 |
| 37866664 | 2024 | circ_SIRT1 upregulates ATG12 to facilitate Imatinib resistance in CML through interacting with EIF4A3. | 0 |
| 34870550 | 2022 | Adaptor SH3BGRL drives autophagy-mediated chemoresistance through promoting PIK3C3 translation and ATG12 stability in breast cancers. | 6 |
| 34904929 | 2022 | ATG12 deficiency results in intracellular glutamine depletion, abrogation of tumor hypoxia and a favorable prognosis in cancer. | 11 |
| 34870550 | 2022 | Adaptor SH3BGRL drives autophagy-mediated chemoresistance through promoting PIK3C3 translation and ATG12 stability in breast cancers. | 6 |
| 34904929 | 2022 | ATG12 deficiency results in intracellular glutamine depletion, abrogation of tumor hypoxia and a favorable prognosis in cancer. | 11 |
| 34089766 | 2021 | LncRNA KCNQ1OT1 as a miR-26a-5p sponge regulates ATG12-mediated cardiomyocyte autophagy and aggravates myocardial infarction. | 9 |
| 34453672 | 2021 | Toxoplasma gondii profilin and tachyzoites RH strain may manipulate autophagy via downregulating Atg5 and Atg12 and upregulating Atg7. | 3 |
| 34723728 | 2021 | LncRNA OIP5-AS1 Promotes the Autophagy-Related Imatinib Resistance in Chronic Myeloid Leukemia Cells by Regulating miR-30e-5p/ATG12 Axis. | 6 |
| 34089766 | 2021 | LncRNA KCNQ1OT1 as a miR-26a-5p sponge regulates ATG12-mediated cardiomyocyte autophagy and aggravates myocardial infarction. | 9 |
| 34453672 | 2021 | Toxoplasma gondii profilin and tachyzoites RH strain may manipulate autophagy via downregulating Atg5 and Atg12 and upregulating Atg7. | 3 |
| 34723728 | 2021 | LncRNA OIP5-AS1 Promotes the Autophagy-Related Imatinib Resistance in Chronic Myeloid Leukemia Cells by Regulating miR-30e-5p/ATG12 Axis. | 6 |
| 31612776 | 2020 | BIRC5/Survivin is a novel ATG12-ATG5 conjugate interactor and an autophagy-induced DNA damage suppressor in human cancer and mouse embryonic fibroblast cells. | 60 |
| 31844253 | 2020 | ATG12 deficiency leads to tumor cell oncosis owing to diminished mitochondrial biogenesis and reduced cellular bioenergetics. | 14 |
| 31989778 | 2020 | PTBP3 promotes malignancy and hypoxia-induced chemoresistance in pancreatic cancer cells by ATG12 up-regulation. | 26 |
Citation
Dessen P
ATG12 (autophagy related 12)
Atlas Genet Cytogenet Oncol Haematol. 2013-09-01
Online version: http://atlasgeneticsoncology.org/gene/53501/atg12-(autophagy-related-12)
